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Metabolic Advantage

product on market Capsule Nature's Way Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 58% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The formula contains essential minerals and vitamins, including iodine and B12, which support thyroid function and energy metabolism. Research provides strong evidence for the roles of zinc, copper, and magnesium in cellular processes. However, the overall evidence coverage for this specific ingredient combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Metabolic Advantage
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
90
Servings
Other Combinations
Product Type
58%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mcg (4167% DV)
41.7× RDA — above typical dose 139 studies (A:1, B:44)
200 mcg (133% DV)
1.3× RDA — within safe limits 245 studies (A:4, B:133)
210 mg (50% DV)
Within RDA (0.5× RDA) 316 studies (A:8, B:159)
6 mg (55% DV)
Within RDA (0.5× RDA) 263 studies (A:6, B:134)
300 mcg (33% DV)
Within RDA (0.3× RDA) 37 studies (A:0, B:11)
2.3 mg (100% DV)
Within RDA (1.0× RDA) 9 studies — no high-quality reviews
100 mcg (222% DV)
2.2× RDA — within safe limits 3 studies — no high-quality reviews
200 mg
Market median: 500.0mg (223 products) 24 studies (A:0, B:1)
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
Multi-Glandular Complex
70 mg
Coffee bean extract
66 mg
Thyroid
8 mg

Other Ingredients

Cellulose Gelatin Ascorbyl Palmitate Silica Titanium Dioxide color
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Take 2 capsules three times daily.

Warnings & Precautions

Keep out of reach of children.

Safety sealed with printed inner seal. Do not use if seal is broken or missing.

If you are pregnant, nursing or taking any medications, consult a healthcare professional before use.

Formulation Notes

Supports a healthy metabolism Promotes thyroid health Enhances energy

Gluten free. No salt, wheat, soy, dairy products, yeast-derived ingredients, or artificial flavors.

Thyroid formula with green coffee & green tea

Metabolism

Additional Information

Since 1969

Metadata

Product Details

UPC / SKU7 63948 04350 7
DSLD Entry Date2021-07-27
Product TypeOther Combinations
FormCapsule
BrandNature's Way
DSLD ID251946
Data Updated2026-04-11
Research

Research Evidence

237
Research Sources
53
Avg Quality
83
Meta Analysis
74
Systematic Review
45
Rct
29
Clinical Trial
2
Guideline
2
Regulatory Source
1
Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021 PubMed DOI
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024 PubMed DOI
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020 PubMed DOI
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024 PubMed DOI
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024 PubMed DOI
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024 PubMed DOI
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023 PubMed DOI
View all evidence for Vitamin B12 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.