🟢 90/100

This product looks safe

  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 40% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Safety Alerts

ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

3 Bi-Layered Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
40% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
200 mg (222% DV)
67 mg (447% DV)
📊 4.5× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 67mg UL 1000mg
Calcium
300 mg (23% DV)
15 mg (136% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
35 mcg (64% DV)
✅ Within RDA (0.6× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.035mg UL 0.4mg
1000 mg
📊 Market median: 420.0mg (227 products)
Median 420.0mg This product: 1000mg
Short-Chain Fatty-Acid–Promoting Prebiotic Blend
400 mg
📊 Market median: 80.0mg (20 products) 📚 334 studies (Tier A: 8, B: 183)
This product: 25mg
Enzyme-Rich Whole Food Blend
25 mg
Live Enzyme Blend
25 mg

Other Ingredients

Microcrystalline Cellulose Di-Calcium Phosphate Hydroxypropyl Methylcellulose Stearic Acid Magnesium Stearate Silica Vegetable Cellulose Beet Juice Tapioca Maltodextrin organic Sunflower Lecithin organic Palm Oil organic Guar Gum

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take 3 tablets daily, or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Keep out of reach of children.

🧪 Formulation Notes

Nutritional support for a healthy GI mucosal lining

GI Natural Total Digestive Wellness by Nature’s Plus is a clinically designed formulation of high-potency L-Glutamine complexed with synergistic and supportive nutrients for a healthy GI mucosal tract.

Optimal digestive health and overall wellness depend on a healthy gut, and GI Natural Total Digestive Wellness not only helps heal the GI tract’s vital mucosal lining but strengthens and vitalizes this tissue. Uniquely formulated as a bi-layered tablet, the fast-release layer optimizes digestive comfort and energy, while the slow-release layer cleanses and rejuvenates. Feel the soothing natural comfort of a healthy digestive tract with the power of GI Natural Total Digestive Wellness!

Free from artificial colors and preservatives. Free from yeast, milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, and soybeans.

Vegetarian

Gluten Free

L-Glutamine Enzymes Probiotics Whole Foods Essential Cofactors

Additional Information

Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 0 97467 04386 2
DSLD Entry Date 2021-07-27
Product Type Other Combinations
Form Tablet or Pill
Brand NaturesPlus
DSLD ID 249677
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
View all evidence for Vitamin C →

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