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NF Formulas PSI Nighttime

product on market Capsule Integrative Therapeutics Safety: 98/100
98/100

This product looks safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 47% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains magnesium and B vitamins, which have moderate evidence for supporting relaxation and sleep quality. Calcium and copper provide additional nutritional support, though the overall evidence coverage for this specific combination is limited. The profile maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for NF Formulas PSI Nighttime
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
47%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg (500% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
20 mg (1000% DV)
15.4× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
Calcium
95 mg (10% DV)
100 mg (25% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
260 mcg (13% DV)
Within RDA (0.3× RDA) 37 studies (A:0, B:11)
Potassium
50 mg (1% DV)
White Willow (Salix alba) Bark Extract 4:1
225 mg
Market median: 250.0mg (60 products) 7 studies (A:0, B:1)
150 mg
Market median: 200.0mg (136 products) 3 studies — no high-quality reviews
Wild Yam
150 mg
120 mg
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)
75 mg
Market median: 80.0mg (136 products)
Hops (Humulus lupulus) Strobile Extract 5:1
60 mg
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)
L-Glutamic Acid
25 mg

Other Ingredients

Vegetable Capsule Citric Acid Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendations: Take 2 capsules at bedtime.

Warnings & Precautions

WARNING: Discontinue use and consult a healthcare practitioner if you have a liver disorder or develop symptoms of liver trouble, such as abdominal pain, dark urine, or jaundice. May impair your ability to drive or operate heavy equipment. Due to additive sedative effect, avoid using with alcohol. May cause drowsiness.

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

Formulation Notes

Contains no sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, preservatives, or ingredients of animal origin.

Additional Information

Used clinically for over 15 years, PSI Nighttime is an effective relaxation formula that supports normal musculoskeletal function and reduces pain and stiffness due to occasional overuse. PSI Daytime also available.

This product contains natural ingredients; color variations are normal.

LI266004.B01 (B010169B)

VEGETARIAN

EVIDENCE-BASED

Supports normal musculoskeletal function

Metadata

Product Details

UPC / SKU8 71791 00189 3
DSLD Entry Date2013-08-23
Product TypeOther Combinations
FormCapsule
DSLD ID24519
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.