NF Formulas PSI Nighttime

product on market Capsule Integrative Therapeutics 🟢 Safety: 98/100
Brand: Integrative Therapeutics
🟢 98/100

This product looks safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • 47% of ingredients have research evidence
C Label Compliance Grade

Product Label

Label for NF Formulas PSI Nighttime
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Safety Alerts

⚠️ Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
47% Evidence Coverage

Supplement Facts — Evidence Check

100 mg (500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.9× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 100mg UL 35mg
20 mg (1000% DV)
📊 15.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 20mg UL 100mg
Calcium
95 mg (10% DV)
100 mg (25% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 100mg
260 mcg (13% DV)
✅ Within RDA (0.3× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.26mg UL 10mg
Potassium
50 mg (1% DV)
White Willow (Salix alba) Bark Extract 4:1
225 mg
160 mg
📊 Market median: 250.0mg (60 products) 📚 7 studies (Tier A: 0, B: 1)
This product: 160mg
150 mg
📊 Market median: 200.0mg (136 products) 📚 3 studies — no high-quality reviews
This product: 150mg
Wild Yam
150 mg
120 mg
📊 Market median: 300.0mg (214 products) 📚 23 studies (Tier A: 0, B: 6)
This product: 120mg
75 mg
📊 Market median: 80.0mg (136 products)
Median 80.0mg This product: 75mg
Hops (Humulus lupulus) Strobile Extract 5:1
60 mg
60 mg
📊 Market median: 300.0mg (214 products) 📚 23 studies (Tier A: 0, B: 6)
This product: 60mg
L-Glutamic Acid
25 mg

Other Ingredients

Vegetable Capsule Citric Acid Magnesium Stearate

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Recommendations: Take 2 capsules at bedtime.

⚠️ Warnings & Precautions

WARNING: Discontinue use and consult a healthcare practitioner if you have a liver disorder or develop symptoms of liver trouble, such as abdominal pain, dark urine, or jaundice. May impair your ability to drive or operate heavy equipment. Due to additive sedative effect, avoid using with alcohol. May cause drowsiness.

If pregnant, nursing, or taking prescription drugs, consult your healthcare practitioner prior to use.

🧪 Formulation Notes

Contains no sugar, salt, yeast, wheat, gluten, corn, soy, dairy products, artificial coloring, artificial flavoring, preservatives, or ingredients of animal origin.

Additional Information

Used clinically for over 15 years, PSI Nighttime is an effective relaxation formula that supports normal musculoskeletal function and reduces pain and stiffness due to occasional overuse. PSI Daytime also available.

This product contains natural ingredients; color variations are normal.

LI266004.B01 (B010169B)

VEGETARIAN

EVIDENCE-BASED

Supports normal musculoskeletal function

Product Details

UPC / SKU 8 71791 00189 3
DSLD Entry Date 2013-08-23
Product Type Other Combinations
Form Capsule
Brand Integrative Therapeutics
DSLD ID 24519
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI Cochrane
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
PubMed DOI
View all evidence for Niacin →

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