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GlucoPlex

product on market Capsule Karuna Safety: 95/100
95/100

This product looks safe

  • Vitamin B3: 1200mg is 34.3× the Tolerable Upper Intake Level (35mg)
  • 57% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

B vitamins B2, B3, and B6 support metabolic function and energy production with strong evidence. Glucosamine is commonly used for joint health, while Betaine-HCl may aid digestion. Overall, clinical evidence for this specific combination is limited, though the profile maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin B3: 1200mg is 34.3× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for GlucoPlex
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
57%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

30 mg (1765% DV)
23.1× RDA — above typical dose 13 studies (A:0, B:1)
1200 mg (6000% DV)
Exceeds UL by 34.3× (UL: 35 mg) 196 studies (A:5, B:63)
45 mg (2250% DV)
34.6× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
1500 mg
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
150 mg
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
150 mg
Market median: 500.0mg (193 products) 7 studies — no high-quality reviews
1.5 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested use for adults: Three capsules daily with meals, in divided doses, or as directed by your health care practitioner.

Warnings & Precautions

WARNING: Persons with a known allergy to shellfish should not use this product.

Formulation Notes

Glucosamine with Niacinamide

This product contains no yeast, wheat, soy, corn, milk, salt, sugar, artificial coloring, preservatives or flavoring.

Additional Information

KARUNA(R) RESPONSIBLE NUTRITION(TM)

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

Keep in a cool, dry place tightly capped.

L911039E12/12

9110-LB6

Metadata

Product Details

DSLD Entry Date2013-10-25
Product TypeOther Combinations
FormCapsule
BrandKaruna
DSLD ID24395
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.