🟢 97/100

This product looks safe

  • Folate: 167mg is 167.0× the Tolerable Upper Intake Level (1.0mg)
  • 73% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 167mg is 167.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

5.2 Gram(s) Serving Size
60 Servings
Other Combinations Product Type
73% Evidence Coverage

Supplement Facts — Evidence Check

Calories
15 Calorie(s)
Total Carbohydrates
4 Gram(s) (1% DV)
25 mg (2083% DV)
📊 20.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 25mg
5 mg (385% DV)
📊 3.8× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 5mg
12.5 mg NE (78% DV)
✅ Within RDA (0.9× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 12.5mg UL 35mg
5 mg (294% DV)
📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 5mg UL 100mg
167 mcg DFE (42% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 167.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 167mg UL 1.0mg
500 mcg (20833% DV)
📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.5mg
50 mcg (167% DV)
✅ 1.7× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.05mg
25 mg (500% DV)
📊 5.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 25mg
12.5 mg
📊 Market median: 180.0mg (239 products) 📚 43 studies (Tier A: 1, B: 19)
This product: 12.5mg UL 400mg

Other Ingredients

Isomalt Maltitol syrup Maltodextrin Soy Protein isolate Natural Flavors Palm Oil Soy Lecithin Citric Acid Malic Acid Fruit and Vegetable Juice Glycerin Pea Protein Sucralose Polydextrose Sunflower Oil

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Sugar Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, enjoy one soft chew daily. Do not take near bedtime.

⚠️ Warnings & Precautions

Contains: Soybeans.

Warning: Consult a physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.

Discontinue use two weeks prior to surgery. Niacin may cause a temporary flushing reaction. Inform your physician of this product's biotin before any lab test. This product contains 12.5 mg of caffeine.

Keep out of reach of chidren.

🧪 Formulation Notes

Metabolism & energy production Immune & nervous system functions

Plus caffeine Berry Smoothie Natural Flavor

No sugar, gluten free.

B-Complex Plus Energy Soft Chews are a convenient alternative to pills and a great addition to your daily nutrition and health regimen. They're packed with B-vitamins, which are essential for carbohydrate metabolism and energy production. Plus, each soft chew has 12.5 mg of caffeine.

These delicious soft chew are gluten and sugar free. Plus, they're individually wrapped, making them easy to take on the go.

Additional Information

60 servings

Store in a cool, dry place.

Our quality commitment to you Since 1935, our mission as the industry leader has been to provide you with the highest-quality nutritional supplements. We continue to stand behind this mission. If you're not 100% satisfied with your purchase, return the unused portion of the product with your receipt within 30 days and we'll either refund your money or find a replacement product that is right for you.

Product Details

UPC / SKU 0 48107 21263 6
DSLD Entry Date 2021-01-22
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand GNC
DSLD ID 243083
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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