🟢 96/100

This product looks safe

  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 78% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
78% Evidence Coverage

Supplement Facts — Evidence Check

20 mg (125% DV)
✅ 1.4× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 20mg UL 35mg
20 mg (1176% DV)
📊 15.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 20mg UL 100mg
680 mcg DFE (170% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 680mg UL 1.0mg
100 mcg (4167% DV)
📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.1mg
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
240 mcg (686% DV)
📊 6.9× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.24mg
📊 Market median: 180.0mg (239 products) 📚 43 studies (Tier A: 1, B: 19)
This product: 150mg UL 400mg
Charge Up Botanical Blend
350 mg
Charge Up Amino Blend
237 mg

Other Ingredients

Hydroxypropyl Methylcellulose Maltodextrin Silica Stearic Acid

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: Take 2 capsules 30 minutes before activity.

⚠️ Warnings & Precautions

Warning: Do not exceed 2 capsules daily.

If you have a medical condition, are on medication, or are pregnant or nursing, please seek the advice of a qualified health care professional before using.

Do not use if bottle seal is broken or missing. Take the product with food if you experience stomach upset. Discontinue use if any serious adverse reaction occurs.

Do not consume more than 200mg of caffeine from all sources in a 4 hour period.

Not recommended for use by children under 18 years of age.

Processed in a facility with products that may contain soy, egg, peanuts, tree nuts, milk, fish, shellfish & wheat.

Keep out of reach of children.

California residents only. Warning: Cancer and reproductive harm www.p65warning.ca.gov

🧪 Formulation Notes

Product contains 150mg of caffeine per serving.

Vegan

Energy

Contains Caffeine

Additional Information

Store in a cool, dry place.

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Product Details

DSLD Entry Date 2021-02-25
Product Type Other Combinations
Form Capsule
Brand Neubria
DSLD ID 242842
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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