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B-Complex with Folic Acid + Vitamin C

product on market Tablet or Pill Rexall Safety: 96/100
96/100

This product looks safe

  • Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
  • 78% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins and Vitamin C, which are supported by strong evidence for their roles in energy metabolism and immune function. These nutrients act as essential cofactors for cellular processes and antioxidant defense. The product maintains a high safety score, indicating a low risk of adverse effects when taken as directed.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for B-Complex with Folic Acid + Vitamin C
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Vitamin
Product Type
78%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
120 mg (133% DV)
5 mg (417% DV)
4.2× RDA — above typical dose 76 studies (A:0, B:33)
5 mg (385% DV)
3.8× RDA — above typical dose 13 studies (A:0, B:1)
25 mg (156% DV)
1.8× RDA — within safe limits 196 studies (A:5, B:63)
5 mg (294% DV)
3.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
666 mcg DFE (167% DV)
Exceeds UL by 666.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
250 mcg (10417% DV)
104.2× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
10 mg (200% DV)
2.0× RDA — within safe limits 2 studies — no high-quality reviews

Other Ingredients

Hypromellose Dicalcium Phosphate Cellulose Stearic Acid Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: For adults, take one (1) tablet daily, preferably with a meal. As a reminder, discuss the supplements and medications you take with your health care providers.

Warnings & Precautions

Warning: If you are pregnant, nursing or taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Tamper resistant: Do not use if seal under cap is broken or missing.

As a reminder, discuss the supplements and medications you take with your health care providers.

Formulation Notes

Important facts you should know B-Complex with Folic Acid + Vitamin C provides a good source of B-vitamins and is essential for the maintenance of healthy nervous tissue and energy metabolism. This formula also contains Vitamin C to support the immune system and helps promote antioxidant activity. Specially formulated to provide a gradual release of vitamins over a prolonged period of time.

No gluten, no yeast, no wheat, no milk, or milk derivatives, no lactose, no sugar, no preservatives, no soy, no artificial color, no artificial flavor, no sodium.

Timed release High potency Energy metabolism and nervous system health

Additional Information

Store at room temperature and avoid excessive heat.

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Metadata

Product Details

UPC / SKU3 01220 29336 5
DSLD Entry Date2020-11-21
Product TypeVitamin
FormTablet or Pill
BrandRexall
DSLD ID239511
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.