Home/ Supplements/ Riboflavin/ Homocystrol + TMG

Homocystrol + TMG

product on market Capsule Douglas Laboratories Safety: 95/100
95/100

This product looks safe

  • Folate: 1.333mg is 1.3× the Tolerable Upper Intake Level (1.0mg)
  • 86% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines B vitamins and choline, which have strong evidence for supporting the metabolism of homocysteine. Riboflavin, B6, folate, and B12 act as essential cofactors in the methylation cycle to maintain cardiovascular and neurological health. Research indicates these ingredients are generally safe and effective for managing homocysteine levels.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 1.333mg is 1.3× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Homocystrol + TMG
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Vegetarian Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
86%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (3846% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (2941% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
1333 mcg (333% DV)
Exceeds UL by 1.3× (UL: 1.0 mg) 226 studies (A:10, B:105)
1000 mcg (41667% DV)
416.7× RDA — above typical dose 139 studies (A:1, B:44)
150 mg
Within RDA (0.3× RDA) 38 studies (A:1, B:7)
50 mg (12% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews

Other Ingredients

Hydroxypropyl Methylcellulose Microcrystalline Cellulose Vegetable Stearate Silica
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: As a dietary supplement, adults take 3 capsules daily or as directed by your health professional.

Warnings & Precautions

Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health professional before using this product.

Keep out of the reach of children.

Use only if safety seal is intact.

Formulation Notes

Gluten-free, Non-GMO

Methylation support

Additional Information

Store in a cool, dry place.

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our manufacturing excellence

Metadata

Product Details

UPC / SKU3 10539 03810 9
DSLD Entry Date2020-08-23
Product TypeOther Combinations
FormCapsule
BrandDouglas Laboratories
DSLD ID232927
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
Compare

Similar Products

Riboflavin
Gematria · Capsule
100
Vitamin B-2 Riboflavin 100 mg
Martin Avenue Pharmacy · Capsule
100
B2 100 mg
Thompson · Capsule
100
Vitamin B-2 100 Milligrams
NutraBio · Capsule
100
Vitamin B2 100 mg
Solgar · Capsule
100
View all Riboflavin products →
Riboflavin research Best Riboflavin All Riboflavin products More from Douglas Laboratories View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.