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BioActive Complete B-Complex

product on market Capsule Life Extension Safety: 93/100
93/100

This product looks safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 73% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins that support energy metabolism and neurological function. Research provides strong evidence for the roles of thiamine, riboflavin, and folate in cellular processes. The ingredient profile maintains a high safety score, though evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for BioActive Complete B-Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Vegetarian Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
73%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg (8333% DV)
83.3× RDA — above typical dose 76 studies (A:0, B:33)
75 mg (5769% DV)
57.7× RDA — above typical dose 13 studies (A:0, B:1)
100 mg NE (625% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
100 mg (5882% DV)
76.9× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
680 mcg DFE (170% DV)
Exceeds UL by 680.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
300 mcg (12500% DV)
125.0× RDA — above typical dose 139 studies (A:1, B:44)
1000 mcg (3333% DV)
33.3× RDA — above typical dose 27 studies (A:0, B:11)
500 mg (10000% DV)
100.0× RDA — above typical dose 2 studies — no high-quality reviews
Calcium
90 mg (7% DV)
100 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
50 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews

Other Ingredients

Vegetable Cellulose Microcrystalline Cellulose Stearic Acid purified Water Silica
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Read the entire label and follow the directions carefully prior to use. Directions: Take two (2) capsules daily with food, or as recommended by a healthcare practitioner.

Warnings & Precautions

Caution: Temporary flushing, itching, rash, or gastric disturbances may occur.

Warnings: Keep out of reach of children.

Do not exceed recommended dose. Do not purchase if outer seal is broken or damaged.

When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Formulation Notes

Gluten free

Non GMO LE Certified

Contains enzymatically active B-vitamins

Additional Information

Non GMO LE Certified

Store tightly closed in cool, dry place.

Metadata

Product Details

UPC / SKU7 37870 19456 9
DSLD Entry Date2020-08-23
Product TypeOther Combinations
FormCapsule
BrandLife Extension
DSLD ID232592
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.