🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 77% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Vegetarian Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
77% Evidence Coverage

Supplement Facts — Evidence Check

2 mg (133% DV)
✅ 1.7× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 2mg
2 mg (118% DV)
✅ 1.5× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 2mg
10 mg (50% DV)
✅ Within RDA (0.7× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 10mg UL 35mg
10 mg (500% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
50 mcg (13% DV)
✅ Within RDA (0.1× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.05mg UL 1.0mg
100 mcg (1667% DV)
📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.1mg
Calcium
50 mg (5% DV)
50 mg (13% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 50mg
📊 Market median: 450.0mg (502 products) 📚 28 studies (Tier A: 0, B: 8)
This product: 30mg
GABA
100 mg
📊 Market median: 400.0mg (142 products) 📚 10 studies (Tier A: 0, B: 2)
This product: 100mg
50 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 50mg
DMAE
25 mg

Other Ingredients

Microcrystalline Cellulose Vegetable Cellulose Vegetable Magnesium Stearate Silicon Dioxide natural Vanilla flavor

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Suggested usage: 1 capsule taken 1 to 2 times daily preferably with meals, or as directed by a healthcare professional.

⚠️ Warnings & Precautions

Note: If you are pregnant or nursing, consult your healthcare professional before using.

Keep out of the reach of children.

Caution: Do not exceed recommended dosage. Avoid driving or operating heavy machinery while taking this product.

Not recommended for pregnant or nursing mothers or children under 18 years of age.

Not recommended for pregnant or nursing mothers or children under 18 years of age. Not for use by individuals with a known medical condition including liver disease, bipolar (manic) depression or anyone taking prescription medications including anti-depressants or MAO inhibitors.

If you have questions about the advisability of taking this product, consult a physician prior to use.

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Do not use if seal under cap is broken or missing.

🧪 Formulation Notes

Promotes calm, balanced & positive mindset

Additional Information

Store in a cool, dry place.

USA Made GMP Good Manufacturing Practice

Product Details

DSLD Entry Date 2020-07-23
Product Type Other Combinations
Form Capsule
DSLD ID 230849
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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