🟢 92/100

This product looks safe

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • 80% of ingredients have research evidence
C Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Safety Alerts

⚠️ Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)

Label Data

2 Vegetable Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
80% Evidence Coverage

Supplement Facts — Evidence Check

500 mg (3125% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 14.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 500mg UL 35mg
0.5 mg (56% DV)
✅ Within RDA (0.6× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 0.5mg UL 10mg
220 mg
📊 Market median: 500.0mg (70 products)
Median 500.0mg This product: 220mg
📊 Market median: 300.0mg (122 products) 📚 22 studies (Tier A: 0, B: 7)
This product: 200mg
30 mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 30mg UL 1200mg

Other Ingredients

Rice Flour Hypromellose Magnesium Stearate Silica

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, take 2 capsules one hour before physical activity or as recommended by your health-care professional. Individual results may vary.

⚠️ Warnings & Precautions

Note: If you are an athlete competing under International Olympic Committee (IOC) or World Anti-Doping Agency (WADA) rules, it should be noted that the IOC and WADA have banned any substance that artificially enhances the uptake, transport, or delivery of oxygen. Because this ban might include Oxydrene NAD+ Enhancer (due to its ability to increase oxygen uptake at peak exercise levels), competitive athletes should check with their trainers and governing bodies before using Oxydrene NAD+ Enhancer in organized athletic competition.

Warning: Do not exceed suggested daily serving. Not for use by individuals under the age of 18 years.

Do not use if pregnant or nursing. Consult your physician before use if you are taking medication or have a medical condition.

Do not use if inner safety seal under cap is broken or missing. Use only as directed.

Keep out of reach of children.

🧪 Formulation Notes

Clinically validated to increase VO2 max!!!

Increases NAD+ levels Increases VO2 max Optimizes systemic oxygen utilization Increases energy Increases endurance Supports cardiovascular health

Additional Information

Product resale allowed only through authorized representatives. International distribution is not authorized without prior written approval.

Store at controlled room temperature: 15 degrees to 30 degrees C / 50 degrees to 86 degrees F

If you or your health-care provider have any questions, or for more information regarding our money-back guarantee, please call our customer service team: 1-800-898-5153.

Product Details

UPC / SKU 8 56528 00169 8
DSLD Entry Date 2020-06-24
Product Type Other Combinations
Form Capsule
DSLD ID 228783
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

Compare Similar Products

View all Niacin products →