MSM Glucosamine Joint Complex by Higher Nature — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
46% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size

Other Combinations Product Type

46% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C

30 mg (38% DV)

Zinc

5 mg (50% DV)

✅ Within RDA (0.5× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 5mg UL 40mg

Copper

250 mcg (25% DV)

✅ Within RDA (0.3× RDA of 0.9 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 0.25mg UL 10mg

Boron

250 mcg

📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews

This product: 0.25mg UL 20mg

Methyl Sulphonyl Methane

450 mg

Glucosamine

150 mg

📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)

This product: 150mg

Ginger rhizome extract

25 mg

📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)

This product: 25mg

Nettle leaf extract

18.75 mg

Celery seed extract

7.5 mg

📊 Market median: 630.0mg (46 products)

Median 630.0mg This product: 7.5mg

Panax ginseng extract

1.5 mg

📊 Market median: 450.0mg (390 products) 📚 155 studies (Tier A: 0, B: 63)

This product: 1.5mg

Kelp

5 mg

Other Ingredients

Methyl Sulphonyl Methane Microcrystalline Cellulose natural Lithothamnion calcarea Glucosamine HCl Vitamin C Magnesium Stearate Ginger rhizome extract Nettle Leaf Extract Zinc Citrate Silicon Dioxide Coating Celery seed extract natural Kelp Sodium Borate Panax ginseng extract Copper Citrate

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Women (not pregnant or lactating) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Directions: Take 1-4 tablets a day with meals building gradually. Do not exceed recommended daily intake.

⚠️ Warnings & Precautions

Warning: Not advisable if pregnant or blood thinning medication.

Initially may cause a laxative effect. This is normal, drink water and reduce intake if symptoms persist.

Storage: Store in a cool, dry place out of reach of children.

Food supplements should not be used as a substitute for a varied and balanced diet and healthy lifestyle.

May contain naturally occurring fish and crustacea.

🧪 Formulation Notes

Free From: Artificial colours, flavourings or preservatives, dairy products, gluten, lactose, soya, sugar, wheat, yeast.

Body health Advanced formula Optimal benefit

With Vitamin C, Copper & Zinc 11 active nutrients

Vegetarian and vegan

With 11 active nutrients including 5 plant extracts Contains the superior form of glucosamine With Zinc to support bones

Vitamin C supports normal collagen formation for normal bones and joints Copper supports normal connective tissue

Additional Information

NRV = Nutrient Reference Value

Storage: Store in a cool, dry place out of reach of children.

This product is not tested on animals.

(Allergens in bold)

Product Details

UPC / SKU 5 031013 102899

DSLD Entry Date 2020-06-24

Product Type Other Combinations

Form Tablet or Pill

Brand Higher Nature

DSLD ID 224720

Data Updated 2026-04-11

Research Evidence

39 Research Sources

50 Avg Quality Score

20 Rct

9 Meta Analysis

4 Clinical Trial

3 Systematic Review

1 Regulatory Source

1 Openfda Safety

B Interventions for the management of temporomandibular joint osteoarthritis

Systematic Review The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

B Glucosamine therapy for treating osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2005

PubMed Cochrane

B Chondroitin for osteoarthritis

Meta Analysis The Cochrane database of systematic reviews 2015

PubMed DOI Cochrane

B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis

Meta Analysis Archives of orthopaedic and trauma surgery 2023

PubMed DOI

B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis

Rct The New England journal of medicine 2006

PubMed

B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review

Systematic Review International journal of molecular sciences 2023

PubMed DOI

B Scientific Opinion on glucosamine and joint health

Regulatory Source EFSA Journal 2009

DOI

B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis

Meta Analysis Computational and mathematical methods in medicine 2022

PubMed DOI

B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib

Rct Annals of the rheumatic diseases 2016

PubMed DOI

B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials

Meta Analysis Journal of orthopaedic surgery and research 2018

PubMed DOI

View all evidence for Glucosamine →