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Bioactive B-Complex

product on market Capsule Vthrive The Vitamin Shoppe Safety: 92/100
92/100

This product looks safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
  • 80% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This complex contains B vitamins that support energy metabolism and neurological function. Research provides strong evidence for the roles of thiamine, riboflavin, and folate in cellular processes. However, the overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Bioactive B-Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Vegetable Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
80%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg (8330% DV)
83.3× RDA — above typical dose 76 studies (A:0, B:33)
100 mg (7690% DV)
76.9× RDA — above typical dose 13 studies (A:0, B:1)
100 mg (630% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
100 mg (5880% DV)
76.9× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg DFE (100% DV)
Exceeds UL by 400.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
500 mcg (20830% DV)
208.3× RDA — above typical dose 139 studies (A:1, B:44)
1000 mcg (3330% DV)
33.3× RDA — above typical dose 27 studies (A:0, B:11)
500 mg (10000% DV)
100.0× RDA — above typical dose 2 studies — no high-quality reviews
100 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
50 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews

Other Ingredients

Vegetable Cellulose Rice Flour Calcium Palmitate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take two(2) vegetable capsules daily.

Warnings & Precautions

Warning: Consult our healthcare provider prior to use if you are pregnant, nursing, taking any medications or have any medical conditions.

Keep out of reach of children.

Tamper evident Do not use if outer seal is broken or missing.

Formulation Notes

Complete B vitamins plus active coenzymes

Energy production Stress support Nervous system support Nutrient metabolism

Non-GMO Gluten-free Soy-free

Vitamins & minerals

Additional Information

Store in a cool, dry place.

Quality Promise Tested & Trusted

Metadata

Product Details

UPC / SKU7 66536 06110 5
DSLD Entry Date2019-12-22
Product TypeOther Combinations
FormCapsule
BrandVthrive The Vitamin Shoppe
DSLD ID208785
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.