🟢 98/100

This product looks safe

  • Manganese: 25mg is 2.3× the Tolerable Upper Intake Level (11mg)
  • 57% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Manganese: 25mg is 2.3× the Tolerable Upper Intake Level (11mg)

Label Data

3 Tablet(s) Serving Size
Other Combinations Product Type
57% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
100 mg (167% DV)
25 mg (125% DV)
✅ 1.8× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 25mg UL 35mg
25 mg (250% DV)
📊 5.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 25mg
25 mg (1250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.3× (UL: 11 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 25mg UL 11mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1000mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 100mg
📊 Market median: 375.0mg (171 products) 📚 30 studies (Tier A: 1, B: 14)
This product: 100mg
MSM
100 mg
📊 Market median: 1000.0mg (2 products)
This product: 100mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 50mg
25 mg
📊 Market median: 200.0mg (136 products) 📚 3 studies — no high-quality reviews
This product: 25mg
📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)
This product: 10mg
10 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 10mg
📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)
This product: 50mg
L-Proline
50 mg

Other Ingredients

Magnesium Stearate Cellulose Vegetable Stearin Dicalcium Phosphate Silica

Label Claims — Verification

All Other
Structure/Function
All Other (100% of products) Structure/Function (89% of products) Nutrient (16% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested Use: As a dietary supplement, adults take three (3) tablets daily with meals, or as directed by a health care professional.

⚠️ Warnings & Precautions

Keep out of reach of children.

🧪 Formulation Notes

Contains no added dairy, yeast, wheat, corn, soy, preservatives, artificial colors or flavors.

We use only the highest quality Chondroitin and Glucosamine Sulfates.

Additional Information

Store in a cool, dry place and away from direct light.

QUALITY AND POTENCY GUARANTEED

"We Make It Better..."

#10091

GDUs (Gelatin Digestive Units) are a measure of the relative strength of digestive aids.

Product Details

DSLD Entry Date 2013-03-25
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 19577
Data Updated 2026-04-11

Research Evidence

39 Research Sources
50 Avg Quality Score
20 Rct
9 Meta Analysis
4 Clinical Trial
3 Systematic Review
1 Regulatory Source
1 Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018
View all evidence for Glucosamine →

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