Amino Replete

product on market Powder Pure Encapsulations 🟢 Safety: 100/100
Brand: Pure Encapsulations
🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 11% of ingredients have research evidence
B Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains essential amino acids like L-Histidine and L-Isoleucine, which are supported by strong evidence for supporting protein synthesis and muscle maintenance. Vitamin B6 serves as a cofactor for amino acid metabolism. Overall, the evidence for these individual components is well-established, though the specific combination's efficacy is less documented.

AI-generated summary based on research evidence. Not medical advice.

Product Label

Label for Amino Replete
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Label Data

9 Gram(s) Serving Size
60 Servings
Other Combinations Product Type
11% Evidence Coverage

Supplement Facts — Evidence Check

Calories
35 Calorie(s)
Total Carbohydrates
5 Gram(s) (2% DV)
2 mg (118% DV)
✅ 1.5× RDA — within safe limits 📚 114 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 2mg UL 100mg
L-Histidine
80 mg
200 mg
📊 Market median: 17.4mg (161 products)
Median 17.4mg This product: 200mg
345 mg
📊 Market median: 17.4mg (161 products)
Median 17.4mg This product: 345mg
250 mg
📊 Market median: 500.0mg (159 products)
Median 500.0mg This product: 250mg
200 mg
📊 Market median: 500.0mg (193 products) 📚 7 studies — no high-quality reviews
This product: 200mg
L-Phenylalanine
175 mg
L-Threonine
161 mg
L-Valine
300 mg
L-Alanine
185 mg
250 mg
📊 Market median: 500.0mg (143 products)
This product: 250mg
439 mg
📊 Market median: 420.0mg (227 products)
Median 420.0mg This product: 439mg
Glycine
102 mg
L-Serine
88 mg
169 mg
📊 Market median: 500.0mg (223 products) 📚 24 studies (Tier A: 0, B: 1)
This product: 169mg
48 mg
📊 Market median: 500.0mg (70 products)
Median 500.0mg This product: 48mg

Other Ingredients

Fructose natural Lemon flavor other Natural flavors Citric Acid hypoallergenic Plant Fiber Luo Han Guo (Momordica grosvenorii) extract

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (98% of products) Structure/Function (89% of products) Nutrient (43% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Recommendations: As a dietary supplement, take 1 scoop daily, mixed with 8 ounces of water or juice, between meals, or as directed by a health professional.

⚠️ Warnings & Precautions

Warning: If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Phenylketonurics: Contains phenylalanine

Keep out of the reach of children.

Use only if safety seal is intact.

🧪 Formulation Notes

Phenylketonurics: Contains phenylalanine

Gluten-free, Non-GMO & Hypoallergenic

Gluten-free, Non-GMO & Hypoallergenic

Additional Information

Store in a cool, dry place.

Packaged by weight, not volume. Settling may occur. Scan to learn about our hypoallergenic supplements Free-form amino acid powder; Support for daily wellness and athletic activity

v4 code: AMR5

Product Details

UPC / SKU 7 66298 11493 4
DSLD Entry Date 2019-02-25
Product Type Other Combinations
Form Powder
Brand Pure Encapsulations
DSLD ID 184274
Data Updated 2026-04-11

Research Evidence

153 Research Sources
55 Avg Quality Score
71 Systematic Review
51 Meta Analysis
19 Rct
6 Clinical Trial
2 Other
2 Regulatory Source
1 Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013
PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009
PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021
PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016
PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020
PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006
PubMed Cochrane
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022
PubMed DOI
View all evidence for Vitamin B6 →

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Vitamin B6 research & evidence Best Vitamin B6 rankings All Vitamin B6 products More from Pure Encapsulations View on NIH DSLD →
DSLD ID: 184274 Fetched: 2026-04-11
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