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Pyridoxine HCL

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100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

Vitamin B6 is essential for protein metabolism and the synthesis of neurotransmitters. There is strong evidence supporting its role in maintaining neurological health and supporting immune function. This ingredient is generally recognized as safe when consumed within recommended daily limits.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Pyridoxine HCL
Open Full PDF View on NIH DSLD →
Details

Label Data

50 mg
Serving Size
500000
Servings
Vitamin
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

41 mg (2057% DV)
31.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)

Other Ingredients

None
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, take 50 mg (1/64 tsp) once or twice daily, depending on individual needs or as directed by physician. For accurate measurement use of a milligram scale is recommended.

Warnings & Precautions

Do not take more than 125mg per day.

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women.

Consult your physician before use.

Keep out of reach of children.

Formulation Notes

Vitamin B6

Free of: Sugar, soy, dairy, yeast, gluten, corn and additives.

Additional Information

Storage: Keep dry, cool & dark

US Standard Measuring Spoons Spoon Size (level) milligrams 1/64 teaspoon 58 1/32 teaspoon 116 1/16 teaspoon 232

Metadata

Product Details

DSLD Entry Date2013-09-25
Product TypeVitamin
FormPowder
DSLD ID23217
Data Updated2026-04-11
Research

Research Evidence

153
Research Sources
55
Avg Quality
71
Systematic Review
51
Meta Analysis
19
Rct
6
Clinical Trial
2
Other
2
Regulatory Source
1
Openfda Safety
A Efficacy of vitamin and antioxidant supplements in prevention of cardiovascular disease: systematic review and meta-analysis of randomised controlled trials
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Homocysteine lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2009 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Exploring the causal associations of micronutrients on urate levels and the risk of gout: A Mendelian randomization study
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
A Pyridoxine (vitamin B6) supplementation during pregnancy or labour for maternal and neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Prophylactic drug management for febrile seizures in children
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy: A Systematic Review
Systematic Review JAMA 2016 PubMed DOI
B The potential role of nutritional components in improving brain function among patients with Alzheimers disease: a meta-analysis of RCT studies
Meta Analysis Neurosciences (Riyadh, Saudi Arabia) 2020 PubMed DOI
B Pyridoxine (vitamin B6) supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B Effect of ginger in the treatment of nausea and vomiting compared with vitamin B6 and placebo during pregnancy: a meta-analysis
Meta Analysis The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2022 PubMed DOI
View all evidence for Vitamin B6 →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.