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Cortisol (Serum)

Hormone Unit: ug/dL

Primary stress hormone; follows diurnal rhythm

Also known as: AM Cortisol

Reference Ranges

Clinical Reference 6.2 – 19.4 ug/dL
Optimal Range 10.0 – 18.0 ug/dL
Critical Range < 3.0 / > 50.0 ug/dL

Morning sample (7-10am)

Related Conditions

Cushings Syndrome High
Chronic Stress High
Addisons Disease Low
Adrenal Insufficiency Low

Food & Lifestyle Recommendations

🍎 Food Avoid late-night caffeine; stabilize blood sugar with balanced meals Caffeine and hypoglycemia spike cortisol
🍎 Food Eat regular meals with adequate salt and protein; support adrenal function Stabilizes fuel for adrenal output
🏃 Exercise Moderate exercise daily; avoid excessive endurance training (raises cortisol chronically) Exercise dose matters
🏃 Exercise Gentle exercise (walking, yoga); avoid overtraining which worsens adrenal output Low cortisol requires restorative movement
😴 Sleep Consistent sleep schedule 10pm-6am; cortisol rhythm needs anchored sleep times Circadian cortisol regulation
🧘 Stress Daily meditation/breathwork (10-20 min); reduces cortisol by 15-25% in RCTs Well-documented stress-reduction effects

Evidence-Backed Supplements

When High

When Low

Questions to Ask Your Doctor

  • Should we do a 24-hr urine cortisol or dexamethasone suppression test? Rules out Cushing's
  • Could this be stress-related or indicate an underlying disorder? Distinguish functional from pathologic
  • Should we test ACTH and do a stimulation test for Addison's? Essential adrenal workup

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