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Nia Plus

product on market Capsule Douglas Laboratories Safety: 98/100
98/100

This product looks safe

  • Niacinamide: 300mg is 8.6× the Tolerable Upper Intake Level (35mg)
  • 27% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines B vitamins and magnesium to support cellular energy production and metabolic function. Research provides strong evidence for the roles of niacin and pantothenic acid in cofactor synthesis, though overall evidence coverage for this specific blend is limited. The profile maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacinamide: 300mg is 8.6× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Nia Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
27%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

30 mg (150% DV)
2.1× RDA — within safe limits 196 studies (A:5, B:63)
300 mg (1500% DV)
Exceeds UL by 8.6× (UL: 35 mg) 196 studies (A:5, B:63)
150 mcg (50% DV)
5.0× RDA — above typical dose 27 studies (A:0, B:11)
100 mg (1000% DV)
20.0× RDA — above typical dose 2 studies — no high-quality reviews
200 mg (50% DV)
Within RDA (0.5× RDA) 316 studies (A:8, B:159)
Potassium
99 mg (2% DV)
50 mg
Market median: 80.0mg (136 products)
400 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
Raw Heart
10 mg
Raw Kidney
5 mg
Raw Liver
5 mg
Raw Spleen
5 mg
Raw Duodenum
5 mg
Raw Pancreas
5 mg
Raw Brain
5 mg

Other Ingredients

Cellulose Gelatin Silica Vegetable Stearate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested Usage: As a dietary supplement, adults take 2 capsules daily or as directed by your healthcare professional.

Warnings & Precautions

Tamper resistant package, do not use if outer seal is missing.

Formulation Notes

This product contains NO yeast, wheat gluten, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Additional Information

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

Formula #7428

Metadata

Product Details

DSLD Entry Date2012-06-01
Product TypeOther Combinations
FormCapsule
BrandDouglas Laboratories
DSLD ID8695
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.