🟢 98/100

This product looks safe

  • Niacinamide: 300mg is 8.6× the Tolerable Upper Intake Level (35mg)
  • 27% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacinamide: 300mg is 8.6× the Tolerable Upper Intake Level (35mg)

Label Data

2 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
27% Evidence Coverage

Supplement Facts — Evidence Check

30 mg (150% DV)
✅ 2.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 30mg UL 35mg
300 mg (1500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 8.6× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 300mg UL 35mg
150 mcg (50% DV)
📊 5.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.15mg
100 mg (1000% DV)
📊 20.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 100mg
200 mg (50% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 200mg
Potassium
99 mg (2% DV)
50 mg
📊 Market median: 80.0mg (136 products)
Median 80.0mg This product: 50mg
400 mg
📊 Market median: 500.0mg (9 products)
This product: 400mg
Raw Heart
10 mg
Raw Kidney
5 mg
Raw Liver
5 mg
Raw Spleen
5 mg
Raw Duodenum
5 mg
Raw Pancreas
5 mg
Raw Brain
5 mg

Other Ingredients

Cellulose Gelatin Silica Vegetable Stearate

Label Claims — Verification

All Other
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested Usage: As a dietary supplement, adults take 2 capsules daily or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Tamper resistant package, do not use if outer seal is missing.

🧪 Formulation Notes

This product contains NO yeast, wheat gluten, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Additional Information

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

Formula #7428

Product Details

DSLD Entry Date 2012-06-01
Product Type Other Combinations
Form Capsule
DSLD ID 8695
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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