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Isotonix OPC-3 (Oligomeric Proanthocyanidins)

product on market Powder Might-A-Mins Spectrum Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 38% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin C and D3 are supported by strong evidence for maintaining immune function and bone health. However, the overall evidence coverage for this specific ingredient profile is very limited at 0.375%. The formulation maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Isotonix OPC-3 (Oligomeric Proanthocyanidins)
Open Full PDF View on NIH DSLD →
Details

Label Data

3.3 Gram(s)
Serving Size
90
Servings
Other Combinations
Product Type
38%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
Total Carbohydrates
1 g
Sugar
1 g
Vitamin C
100 mg (167% DV)
200 IU (50% DV)
Within RDA (0.3× RDA) 608 studies (A:16, B:251)
16.5 IU (55% DV)
Within RDA (0.7× RDA) 179 studies (A:3, B:90)
75 mcg (25% DV)
2.5× RDA — within safe limits 27 studies (A:0, B:11)
Calcium
200 mg (20% DV)
75 mg (19% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
Potassium
50 mg
Pine bark extract
20 mg
Market median: 100.0mg (284 products) 10 studies (A:0, B:4)
Grape skin extract
12.5 mg
Market median: 100.0mg (120 products)
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
Market median: 100.0mg (173 products)

Other Ingredients

Citric Acid grape juice powder Malic Acid Fructose Grape flavor raspberry juice powder grape skin extract Raspberry flavor rebaudioside A Silicon Dioxide Lo Han extract Maltodextrin
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions for use: Ages 2-3: Pour 1 level, white bottle capful of powder into the overcap. Add water to the line on the overcap (2 fl. oz./60 mL) and stir. Take once daily or as directed by your healthcare provider. Ages 4 and older: Take 2 capfuls daily. Maximum absorption occurs when taken on an empty stomach. This product is isotonic only if the specified amounts of powder and water are used.

Warnings & Precautions

Warning: If you are using prescription drugs, have an ongoing medical condition, or if you are pregnant or breastfeeding, you should consult your healthcare provider before using this product.

KEEP OUT OF THE REACH OF CHILDREN.

Do not use if safety seal is broken or missing.

Formulation Notes

This product contains no added wheat, soy, yeast, gluten, artificial flavor, starch, salt, preservatives or milk.

Additional Information

PYCNOGENOL(R) (Pine Trees) NATURES SUPER ANTIOXIDANT

Store in a cool, dry place.

REV 1109

Provides strong antioxidant defense Helps maintain brain health Supports the production of neurotransmitters Powerful free-radical scavenger

Metadata

Product Details

DSLD Entry Date2012-04-26
Product TypeOther Combinations
FormPowder
DSLD ID8176
Data Updated2026-04-11
Research

Research Evidence

14
Research Sources
50
Avg Quality
9
Rct
2
Meta Analysis
2
Clinical Trial
1
Systematic Review
B Low Dose Monacolin K Combined with Coenzyme Q10, Grape Seed, and Olive Leaf Extracts Lowers LDL Cholesterol in Patients with Mild Dyslipidemia: A Multicenter, Randomized Controlled Trial
Rct Nutrients 2023 PubMed DOI
B Efficacy of Bilberry and Grape Seed Extract Supplement Interventions to Improve Glucose and Cholesterol Metabolism and Blood Pressure in Different Populations-A Systematic Review of the Literature
Systematic Review Nutrients 2021 PubMed DOI
B The effect of grape seed extract on cardiovascular risk markers: a meta-analysis of randomized controlled trials
Meta Analysis Journal of the American Dietetic Association 2011 PubMed DOI
B The impact of grape seed extract treatment on blood pressure changes: A meta-analysis of 16 randomized controlled trials
Meta Analysis Medicine 2016 PubMed DOI
B Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers
Rct Nutrients 2021 PubMed DOI
C Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial
Rct The British journal of nutrition 2016 PubMed DOI
C Effect of grape seed extract on blood pressure in subjects with the metabolic syndrome
Rct Metabolism: clinical and experimental 2009 PubMed DOI
C Grape seed extract supplementation along with a restricted-calorie diet improves cardiovascular risk factors in obese or overweight adult individuals: A randomized, placebo-controlled trial
Rct Phytotherapy research : PTR 2021 PubMed DOI
C The effect of polyphenol-rich chardonnay seed supplements on peripheral endothelial function.
Rct European journal of nutrition PubMed DOI
C The effects of grape seed extract supplementation on cardiovascular risk factors, liver enzymes and hepatic steatosis in patients with non-alcoholic fatty liver disease: a randomised, double-blind, placebo-controlled study.
Rct BMC complementary medicine and therapies PubMed DOI
View all evidence for Grape Seed →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.