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Sedaplex

product on market Capsule Integrative Therapeutics Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 55% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins and minerals such as magnesium and calcium, which are supported by strong evidence for supporting cellular energy and nerve function. These ingredients play essential roles in metabolic processes and neuromuscular health. However, the overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Sedaplex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
55%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
25 mg (125% DV)
1.8× RDA — within safe limits 196 studies (A:5, B:63)
15 mg (750% DV)
11.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
Calcium
25 mg (3% DV)
25 mg (6% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)
Hops (Humulus lupulus) strobile extract
150 mg
Jujube seed extract
150 mg
Market median: 250.0mg (60 products) 7 studies (A:0, B:1)
Skullcap (Scutellaria lateriflora) aerial parts extract
125 mg
100 mg
Market median: 200.0mg (358 products) 9 studies (A:0, B:2)

Other Ingredients

Hydroxypropyl Methylcellulose Cellulose Calcium Laurate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendations: For daytime use, take 1 to 2 capsules daily or for nighttime use, take 1 to 2 capsules one-half hour before bedtime, or as recommended by your healthcare professional.

Warnings & Precautions

Warning: Do not use this product if pregnant or nursing.

Do not use alcohol while using this product as it has sedative properties. Do not operate heavy equipment/machinery or drive while using this product.

If taking prescription drugs or tranquilizers, consult your healthcare professional prior to use.

Formulation Notes

Contains no sugar, salt, yeast, wheat, gluten, soy, dairy products, artificial colors, flavors, preservatives or ingredients of animal origin.

Additional Information

LZ246004.C01 B010134C

Restful sleep support

Metadata

Product Details

UPC / SKU8 71791 00293 7
DSLD Entry Date2017-09-21
Product TypeOther Combinations
FormCapsule
BrandIntegrative Therapeutics
DSLD ID78335
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.