🟢 96/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 50% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label Data

16.9 fl. Oz. Serving Size
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Carbohydrates
3 Gram(s) (1% DV)
50 mg (250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
Sodium
170 mg (7% DV)
Potassium
65 mg (2% DV)
2000 mg
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 2000mg
📊 Market median: 180.0mg (239 products) 📚 43 studies (Tier A: 1, B: 19)
This product: 250mg UL 400mg
100 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 100mg
White Willow
50 mg
📊 Market median: 983.0mg (16 products) 📚 7 studies (Tier A: 0, B: 1)
This product: 50mg

Other Ingredients

Water Natural and Artificial flavors Citric Acid Disodium Phosphate Malic Acid Sucralose Potassium Sorbate Acesulfame Potassium

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Sugar Free

Product Information

📋 Directions for Use

SHAKE WELL BEFORE USE

DIRECTIONS: For adults, do not exceed one (1) bottle per 24-hour period. Start with half the recommended dosage to assess individual tolerance.

⚠️ Warnings & Precautions

WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18, FOR THOSE SENSITIVE TO CAFFEINE, OR FOR PREGNANT OR LACTATING WOMEN.

WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18, FOR THOSE SENSITIVE TO CAFFEINE, OR FOR PREGNANT OR LACTATING WOMEN.

Do not exceed recommended dose. Increasing frequency of intake will not improve results and may cause adverse reactions.

This product contains synephrine and caffeine. Do not consume additional sources of synephrine or caffeine, which may cause adverse effects. Use of this product may make skin sensitive to sunlight and UV light, which could result in sunburn or skin rash after several days of use. Limit exposure to the sun or any indoor tanning equipment including beds, lamps or booths.

Consult a doctor before using this product if you are using any medications or remedies, especially antidepressants or monoamine oxidase inhibitors (MAOI), stimulants, any dietary supplement (Yohimbe or St. John’s Wort), or any over-the-counter drug including allergy, asthma, cough/cold or weight control products.

Avoid this product if you are allergic to aspirin.

Avoid this product if you have high blood pressure, arrhythmias, glaucoma, seizures, ulcer, difficulty urinating, an enlarged prostate, diabetes or a thyroid, blood, liver or eating disorder. Consult a doctor before use if you are at risk for, have, have had or have a family history of heart or cardiovascular disease, stroke, recurrent headaches, depression or other psychiatric condition. Discontinue use and call a doctor immediately if you experience any adverse reaction such as dizziness, headache, rapid or irregular heartbeat, chest pain, shortness of breath, nausea, noticeable changes in behavior, loss of consciousness, increased blood pressure, sleeplessness, anxiety, or skin reactions. Limit use to six weeks with a break of one week. Discontinue use two weeks prior to surgery.

KEEP OUT OF REACH OF CHILDREN.

TAMPER RESISTANT: DO NOT USE IF CAP IS BROKEN.

🧪 Formulation Notes

This product contains synephrine and caffeine.

FREE OF SUGAR & ARTIFICIAL COLOR

~TAURINE ~THEANINE ~CAFFEINE

With Advantra Z Synephrine

Additional Information

Our Next Generation ThermoRush contains a combination of premium ingredients designed to get you ready and keep you focused for exercise.* ThermoRush boosts energy, stimulates the neuromuscular system, helps increase body temperature and supports mental focus.*

STORE UNOPENED CONTAINER AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.

REFRIGERATE AFTER OPENING

CA CASH REFUND ME 5 cents

59438 00A B59438 CA5

Pre-workout

Naturally & artificially flavored

Product Details

UPC / SKU 7 86560 59438 7
DSLD Entry Date 2016-10-22
Product Type Other Combinations
Form Liquid
Brand MET-Rx
DSLD ID 65841
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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