🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 70% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

7.5 Gram(s) Serving Size
30 Servings
Other Combinations Product Type
70% Evidence Coverage

Supplement Facts — Evidence Check

Calories
25 Calorie(s)
Total Carbohydrates
6 Gram(s) (2% DV)
3 mg (200% DV)
✅ 2.5× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 3mg
4 mg (235% DV)
📊 3.1× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 4mg
13 mg (65% DV)
✅ Within RDA (0.9× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 13mg UL 35mg
6 mg (300% DV)
📊 4.6× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 6mg UL 100mg
300 mcg (75% DV)
✅ Within RDA (0.7× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.3mg UL 1.0mg
120 mcg (2000% DV)
📊 50.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.12mg
5 mg (33% DV)
✅ Within RDA (0.5× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 5mg UL 40mg
Brainstrong Proprietary Blend (Combination)
715 mg

Other Ingredients

Molasses powder Apple juice powder Natural flavors Silicon Dioxide Sodium Chloride Malic Acid Stevia (Stevia rebaudiana) leaf extract

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Stir one packet into approximately 6 fl oz room-temperature water, to taste, until completely dissolved. Add ice if desired. To receive optimum benefits from Ionix Supreme, drink once or twice daily. May also be enjoyed as a warm tea.

⚠️ Warnings & Precautions

Note: If you are pregnant, breastfeeding, or taking medication, consult your physician before using this product.

Discontinue use if adverse reaction occurs.

🧪 Formulation Notes

No artificial stimulants

Additional Information

By taking Ionix Supreme every day, you may enjoy long-term adaptogenic, stress coping and body-balancing benefits. Best if used as part of your Isagenix system.

Achieve peak mental and physical performance with Ionix Supreme. This drink contains many of our planet's finest natural ingredients to support your body's energy, stamina and health.

New super charged formula

Nature's answer for optimal health

30 packets x 0.26 oz (7.5 g)

A

Buffers the body from stress Support for improved energy, clarity and focus

Store in a cool, dry place.

3900976.761-00 40012

NEW Convenient single serve packets

Product Details

UPC / SKU 351761
DSLD Entry Date 2016-06-24
Product Type Other Combinations
Form Powder
Brand Isagenix
DSLD ID 60819
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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