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Mood Aid With 5-HTP & St. John's Wort

product on market Capsule Nature's Way Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 75% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines B vitamins with St. John's Wort to support neurological function and mood regulation. Research provides moderate evidence that St. John's Wort may assist with mild depressive symptoms. However, overall evidence coverage for this specific ingredient profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Mood Aid With 5-HTP & St. John's Wort
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

250 mcg (17% DV)
Within RDA (0.2× RDA) 76 studies (A:0, B:33)
284 mcg (17% DV)
Within RDA (0.2× RDA) 13 studies (A:0, B:1)
3.33 mg (17% DV)
Within RDA (0.2× RDA) 196 studies (A:5, B:63)
330 mcg (17% DV)
Within RDA (0.3× RDA) 114 studies (A:3, B:35)
Market median: 300.0mg (240 products) 20 studies — no high-quality reviews
Skullcap
100 mg
Market median: 450.0mg (390 products) 160 studies (A:0, B:63)
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)

Other Ingredients

Gelatin Cellulose Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommendation: Take 1 capsule three times daily, preferably with food.

Warnings & Precautions

Caution: Do not use while taking any prescription drug without seeking advice from a healthcare professional.

Avoid excessive exposure to UV radiation (e.g., sunlight; tanning) while using the product.

Not recommended for use by pregnant or lactating women.

Keep out of reach of children.

Freshness & safety sealed with printed outer shrinkwrap and printed inner seal. Do not use if either seal is broken or missing.

Additional Information

SATISFACTION GUARANTEED.

LN79280.100 (BLK8318) R/0

PREMIUM FORMULA

POSITIVE MOOD

Certified 471 mg

Nature's Way(R)

Metadata

Product Details

UPC / SKU0 33674 79280 3
DSLD Entry Date2014-12-29
Product TypeOther Combinations
FormCapsule
BrandNature's Way
DSLD ID40662
Data Updated2026-04-11
Research

Research Evidence

43
Research Sources
48
Avg Quality
16
Meta Analysis
14
Systematic Review
7
Rct
4
Regulatory Source
1
Clinical Trial
1
Openfda Safety
B St John's wort for major depression
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
B Clinical use of Hypericum perforatum (St John's wort) in depression: A meta-analysis
Meta Analysis Journal of affective disorders 2017 PubMed DOI
B A systematic review of St. John's wort for major depressive disorder
Meta Analysis Systematic reviews 2016 PubMed DOI
B St John's wort for depression
Systematic Review The Cochrane database of systematic reviews 2000 PubMed
B Efficacy of Pharmacological Interventions in Milder Depression: A Systematic Review and Meta-Analysis
Meta Analysis Neuropsychopharmacology reports 2025 PubMed DOI
B St John's wort for depression
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
C St John's wort for depression: meta-analysis of randomised controlled trials
Meta Analysis The British journal of psychiatry : the journal of mental science 2005 PubMed
C The effect of Hypericum perforatum on postmenopausal symptoms and depression: A randomized controlled trial
Rct Complementary therapies in medicine 2019 PubMed DOI
C Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks
Rct BMJ (Clinical research ed.) 1999 PubMed
C Hypericum perforatum as a cognitive enhancer in rodents: A meta-analysis
Meta Analysis Scientific reports 2016 PubMed DOI
View all evidence for St Johns Wort →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.