Home/ Supplements/ Riboflavin/ SynaQuell

SynaQuell

product on market Powder Thorne Safety: 98/100
98/100

This product looks safe

  • Nicotinamide Riboside Hydrogen Malate: 207.5mg is 5.9× the Tolerable Upper Intake Level (35mg)
  • 33% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Magnesium and riboflavin are supported by moderate evidence for supporting neurological function and energy metabolism. L-leucine is recognized for its role in protein synthesis and muscle maintenance. Overall, the evidence coverage for this specific ingredient combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Nicotinamide Riboside Hydrogen Malate: 207.5mg is 5.9× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for SynaQuell
Open Full PDF View on NIH DSLD →
Details

Label Data

7.8 Gram(s)
Serving Size
30
Servings
Other Combinations
Product Type
33%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
23 Calorie(s)
Total Carbohydrates
1 Gram(s) (1% DV)
25 mg (1923% DV)
19.2× RDA — above typical dose 13 studies (A:0, B:1)
59 mg (14% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
1.25 Gram(s)
Market median: 17.4mg (161 products)
625 mg
Market median: 17.4mg (161 products)
L-Valine
625 mg
Beta-Hydroxybutyrate
500 mg
Glutathione, Reduced
250 mg
Exceeds UL by 5.9× (UL: 35 mg) 196 studies (A:5, B:63)
Meriva
125 mg
Market median: 750.0mg (447 products) 393 studies (A:18, B:204)
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)
Ubiqsome
50 mg
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews

Other Ingredients

Citric Acid Flavors Rebaudioside A Carboxymethylcellulose Gum
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Mix 2 scoops with at least 8 ounces of water one to two times daily or as recommended by your health-care practitioner.

Warnings & Precautions

Tamper evident: Use only if bottle is sealed.

Warning: If pregnant or nursing, do not use this product.

Formulation Notes

Sports Performance Brain/Nerves

Gluten free

This product uses Indena S.p.A.'s curcumin phytosome (Meriva) and coenzyme Q10 phytosome (Ubiqsome).

Additional Information

Store tightly sealed in a cool, dry place.

Manufactured in the USA using US & Imported Ingredients NSF Certified Sport

T Exclusive

Metadata

Product Details

UPC / SKU6 93749 01318 1
DSLD Entry Date2025-08-22
Product TypeOther Combinations
FormPowder
BrandThorne
DSLD ID337875
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
Compare

Similar Products

Riboflavin Vitamin B2 USP
PureBulk.com · Powder
100
Riboflavin 5 Phosphate Vitamin B2
PureBulk.com · Powder
100
Vitamin B2 Powder
Dr. Clark Research Association Dr. Clark Zentrum · Powder
100
Riboflavin (Vitamin B2)
BulkSupplements.com · Powder
100
Riboflavin (Vitamin B2)
BulkSupplements.com · Powder
100
View all Riboflavin products →
Riboflavin research Best Riboflavin All Riboflavin products More from Thorne View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.