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OSAplex

product on market Capsule XYMOGEN Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 57% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This profile includes calcium, phosphorus, and vitamin D3, which have strong evidence for supporting bone mineralization and skeletal health. Choline and silicon provide additional metabolic and connective tissue support, though evidence for these specific roles is more limited. The formulation maintains a high safety profile.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for OSAplex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Multi-Vitamin and Mineral (MVM)
Product Type
57%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

60 mg (11% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
3 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
50 mcg (250% DV)
3.3× RDA — above typical dose (UL: 0.1 mg) 608 studies (A:16, B:251)
Calcium
550 mg (42% DV)
198 mg (16% DV)
Within RDA (0.3× RDA) 13 studies (A:0, B:3)
Microcrystalline Hydroxyapatite Concentrate
2.2 Gram(s)
Microcrystalline Hydroxyapatite
1.32 Gram(s)

Other Ingredients

Hypromellose Water Stearic Acid Magnesium Stearate Medium Chain Triglyceride Oil Silica Microcrystalline Cellulose Hypromellose Water Water, Purified
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Consume the contents of one packet with a meal, one to two times daily, or as directed by your healthcare professional.

Warnings & Precautions

Consult your healthcare professional prior to use. Do not use if packet is damaged. The labeling on this product does not comply with California's Proposition 65. Therefore, this product may not be sold in California.

Individuals taking medication should discuss potential interactions with their healthcare professional.

Storage: Keep closed in a cool, dry place out of reach of children.

Formulation Notes

Vegetarian Caps

OSAplex is a comprehensive, convenient, and cost-effective dietary supplement that supports healthy bones, cartilage, and ligaments. Bone is composed of a calcium-based mineral complex and an organic material known as collagen. A somewhat flexible and fibrous protein, collagen appears to be a key factor in a bone's ability to withstand sudden impact. The quantity and health of collagen determines the bone's "toughness", while the mineral content determines its strength and stiffness.

Each packet provides the following: two capsules containing a combination of microcrystalline hydroxyapatite concentrate (MCHC) and Vitamin D3, along with one capsules of choline-stabilized orthosilicic acid (ch-OSA). OSAplex contains choline-stabilized orthosilicic acid, a well-absorbed form of silicon. Silicon-dependent enzymes link together single chains of amino acids to synthesize collagen fibers. The surfaces of these collagen fibers act as the binding sites for the MCHC. The more surface area available to the MCHC to bind to, the more flexible the bone. MCHC, a proprietary, standardized, safe, bovine-sourced bone extract from New Zealand, contains a crystalline calcium and phosphorus matrix in the ideal physiological ratio of 2:1, plus bioactive growth factors and type I collagen. As a source of calcium, MCHC contributes to the production and maintenance of bone structure, a function supported by Vitamin D3. Amino acids, glycosaminoglycans, and a broad range of essential trace elements are also present. Combining ch-OSA and MCHC with Vitamin D3 results in a unique package that addresses the quantity and quality of bone and supports overall bone strength and health. Each packet contains: Two microcrystalline hydroxyapatite concentrate with Vitamins D3 capsules and one choline-stabilized orthosilicic acid capsule.

Formulated to exclude: Wheat, gluten, yeast, soy, dairy products, fish, shellfish, peanuts, tree nuts, egg, sesame, ingredients derived from genetically modified organisms (GMOs), artificial colors, and artificial sweeteners.

Supports Total Bone Health and Strength

Additional Information

GMP Compliant Third-Party Verified

Storage: Keep closed in a cool, dry place out of reach of children.

ePV (ePedigree Verification)

Scan this code to learn more! XYMOGEN supports the initiative Clean seas Turn the tide on plastic Xymogen is committed to reducing the amount of plastics used throughout our business, particularly in the packaging of our products. With our participation in the United Nations Environment Programme Clean Seas initiative, we strive to positively decrease our environmental footprint, providing results that can ultimately: Help free the ocean of litter, making it safer for millions of marine animals. Reduce the use of non-renewable resources. Keep wild-caught seafood healthy and safe to eat. Protect maritime economies such as organic fishing, tourism, and recreation. We are doing our part to make a world of difference. How are you making an impact? #CleanSeas

Metadata

Product Details

UPC / SKU8 71149 00236 7
DSLD Entry Date2025-09-25
Product TypeMulti-Vitamin and Mineral (MVM)
FormCapsule
BrandXYMOGEN
DSLD ID335537
Data Updated2026-04-11
Research

Research Evidence

28
Research Sources
47
Avg Quality
11
Clinical Trial
8
Rct
2
Guideline
2
Meta Analysis
2
Regulatory Source
1
Systematic Review
1
Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024 PubMed DOI
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026 PubMed DOI
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022 PubMed DOI
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011 DOI
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition PubMed DOI
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition PubMed DOI
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013 PubMed DOI
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007 PubMed
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.