B Activ by XYMOGEN — Ingredients, Evidence & Safety

🟢 96/100

This product looks safe

Niacin: 140mg is 4.0× the Tolerable Upper Intake Level (35mg)
80% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 140mg is 4.0× the Tolerable Upper Intake Level (35mg)

Label Data

1 Capsule(s) Serving Size

30 Servings

Other Combinations Product Type

80% Evidence Coverage

Supplement Facts — Evidence Check

Thiamine

20 mg (1667% DV)

📊 16.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 20mg

Riboflavin

20 mg (1538% DV)

📊 15.4× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 20mg

Niacin

140 mg (875% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 4.0× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 140mg UL 35mg

Vitamin B6

20 mg (1176% DV)

📊 15.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 20mg UL 100mg

Quatrefolic

680 mcg DFE (170% DV)

Vitamin B12

400 mcg (16667% DV)

📊 166.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.4mg

Biotin

400 mcg (1333% DV)

📊 13.3× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.4mg

Pantothenic Acid

150 mg (3000% DV)

📊 30.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 150mg

Choline

30 mg (5% DV)

✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 30mg UL 3500mg

Benfotiamine

20 mg

📊 16.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 20mg

Other Ingredients

Hypromellose Water Stearic Acid Magnesium Stearate Silica

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) No Allergies Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take one capsule daily, or as directed by your healthcare professional.

⚠️ Warnings & Precautions

Consult your healthcare professional prior to use.

Individuals taking medication should discuss potential interactions with their healthcare professional.

Storage: Keep closed in a cool, dry place out of reach of children.

🧪 Formulation Notes

B Activ is a full-spectrum B-vitamin formula complexed with choline and benfotiamine that features premium vitamin forms selected for their biological activity profiles.

This formula supports adrenal and neurological health and provides important cofactors for metabolic and stress-related biochemical pathways.

Formulated to exclude: Wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, sesame, ingredients derived from genetically modified organisms (GMOs), artificial colors, and artificial sweeteners.

Vegetarian Caps

B Complex With Benfotiamine and Quatrefolic

Professional Formulas

Additional Information

Storage: Keep closed in a cool, dry place out of reach of children.

GMP Compliant Third-Party Verified

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Product Details

UPC / SKU 7 22537 51281 7

DSLD Entry Date 2025-09-25

Product Type Other Combinations

Form Capsule

Brand XYMOGEN

DSLD ID 335427

Data Updated 2026-04-11

Research Evidence

100 Research Sources

56 Avg Quality Score

48 Systematic Review

30 Meta Analysis

13 Rct

6 Clinical Trial

1 Cochrane Review

1 Regulatory Source

B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol

Systematic Review The Cochrane database of systematic reviews 2013

PubMed DOI Cochrane

B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials

Systematic Review Nutritional neuroscience 2023

PubMed DOI

B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis

Meta Analysis BMJ open 2022

PubMed DOI

B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024

PubMed DOI

B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis

Systematic Review Intensive care medicine 2022

PubMed DOI

B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis

Meta Analysis Pain medicine (Malden, Mass.) 2020

PubMed DOI

B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis

Meta Analysis Critical care medicine 2021

PubMed DOI

B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2022

PubMed DOI

B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis

Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023

PubMed DOI

B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse

Systematic Review The Cochrane database of systematic reviews 2004

PubMed Cochrane

View all evidence for Thiamine →