🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 64% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
120 Servings
Other Combinations Product Type
64% Evidence Coverage

Supplement Facts — Evidence Check

25 mg (2083% DV)
📊 20.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 25mg
25 mg (1923% DV)
📊 19.2× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 25mg
15 mg NE (94% DV)
✅ 1.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 15mg UL 35mg
25 mg (1471% DV)
📊 19.2× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 25mg UL 100mg
Quatrefolic
200 mcg DFE (50% DV)
MecobalActive
250 mcg (10417% DV)
500 mcg (1667% DV)
📊 16.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.5mg
125 mg (2500% DV)
📊 25.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 125mg
60 mg (11% DV)
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 60mg UL 3500mg
75 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 75mg
📊 Market median: 500.0mg (9 products)
This product: 15mg

Other Ingredients

Microcrystalline Cellulose Hydroxypropyl Methylcellulose Hydroxypropyl Cellulose Stearic Acid Croscarmellose Sodium Magnesium Stearate Silicon Dioxide Guar Gum Xanthan Gum Sunflower Oil Dicalcium Phosphate

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested use: As a nutritional supplement, take 1 tablet daily. Or use as directed by your healthcare professional.

⚠️ Warnings & Precautions

Should not be used if tamper-evident seal is broken.

Keep out of reach of children.

🧪 Formulation Notes

Inactive forms of B-vitamins require conversion in the liver before they can be used by the body. Activated B w/SRT provides only the ready-to-use, active form of each B-vitamin in a time-release formula, so no conversion is needed. Quatrefolic VitaCholine

Sustained release technology 8 hours Supports healthy nervous system and energy production

Non GMO Gluten free Soy free

Vegan Label Claim Verified

Additional Information

Need more? Call 1-888-352-5050 or visit jigsawhealth.com Please recycle

Product of the U.S.A. with select ingredients thoughtfully curated from around the world.

Store in a cool, dry place.

Vegan

Product Details

UPC / SKU 8 76634 00018 7
DSLD Entry Date 2025-09-25
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 334960
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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