Mood Positive 5-HTP

product on market Tablet or Pill Natrol 🟢 Safety: 94/100
Brand: Natrol
🟢 94/100

This product looks safe

  • Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)
  • 83% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size
50 Servings
Other Combinations Product Type
83% Evidence Coverage

Supplement Facts — Evidence Check

10 mg (588% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
340 mcg DFE (85% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 340.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 340mg UL 1.0mg
50 mcg (2083% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
Calcium
135 mg (10% DV)
50 mg
📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 50mg
50 mg
📊 Market median: 200.0mg (358 products) 📚 9 studies (Tier A: 0, B: 2)
This product: 50mg

Other Ingredients

Microcrystalline Cellulose Stearic Acid Silicon Dioxide Magnesium Stearate Cellulose Gum Methylcellulose Glycerin

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Adult (18 - 50 Years) No Allergies Dairy Free

Product Information

📋 Directions for Use

Suggested use: Adults, take 1 tablet 1-2 times daily with a meal.

⚠️ Warnings & Precautions

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, or are taking medication or have a medical condition; including drugs for depression, migraines, Parkinson's disease or psychiatric disorders.

Warning: Consult a healthcare professional before using this product if you are pregnant, nursing, under the age of 18, or are taking medication or have a medical condition; including drugs for depression, migraines, Parkinson's disease or psychiatric disorders. Keep out of reach of children.

Do not use with other supplements containing L-Tryptophan or 5-HTP. If adverse reactions occur, discontinue use.

Do not use if safety seal is damaged or missing.

🧪 Formulation Notes

Natrol Mood Positive 5-HTP: Helps support a balanced mood Vitamin B6, Vitamin B12 and Folic Acid support brain and neurological health

Mood + stress

100% Drug free

5-HTP promotes production of serotonin, which is associated with general well-being L-Theanine supports alpha brain wave formation, which is associated with relaxation

No: Milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat, soybeans, sesame.

Additional Information

Store in a cool, dry place.

Product Details

UPC / SKU 0 47469 05233 1
DSLD Entry Date 2025-06-25
Product Type Other Combinations
Form Tablet or Pill
Brand Natrol
DSLD ID 332299
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
PubMed Cochrane
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
PubMed Cochrane
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
PubMed DOI
View all evidence for 5 Htp →

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