Home/ Supplements/ 5 Htp/ Griffonia 5-HTP

Griffonia 5-HTP

product on market Tablet or Pill HBC Protocols Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · grounded in 1 source · methodology

5-HTP serves as a precursor to serotonin, while Vitamin B6 acts as a cofactor in its synthesis. There is moderate evidence suggesting these ingredients may support mood regulation and sleep quality. However, overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Griffonia 5-HTP
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
60
Servings
Other Combinations
Product Type
100%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
20 mg (2000% DV)
15.4× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)

Other Ingredients

Calcium Carbonate Cellulose Stearic Acid Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Adults take 2-10 tablets daily or as directed by a physician

Warnings & Precautions

Excessive dosages may cause drowsiness.

Caution: Seek physician’s advice before using if pregnant or lactating. Do not use if concurrently taking MAO inhibitor or other antidepressants.

Do not use for cases of severe depression.

Not for use by preadolescent children.

Additional Information

50 mg

5-HTP has been determined to be a bio chemical precurser to the neurotransmitter serotonin, and also to the circadian rhythm regulator melatonin.

Metadata

Product Details

UPC / SKU6 79840 54180 8
DSLD Entry Date2017-07-25
Product TypeOther Combinations
FormTablet or Pill
DSLD ID74946
Data Updated2026-04-11
Research

Research Evidence

21
Research Sources
53
Avg Quality
11
Systematic Review
6
Rct
4
Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018 PubMed DOI
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002 PubMed
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025 PubMed DOI
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023 PubMed
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025 PubMed DOI
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010 PubMed
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020 PubMed DOI
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025 PubMed DOI
View all evidence for 5 Htp →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.