🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Tablet(s) Serving Size
Amino acid/Protein Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

📊 Market median: 100.0mg (116 products) 📚 15 studies (Tier A: 0, B: 3)
This product: 200mg

Other Ingredients

Microcrystalline Cellulose Hypromellose Stearic Acid Silicon Dioxide

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (78% of products) Nutrient (52% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 1 tablet daily.

⚠️ Warnings & Precautions

Caution: For adults only.

Not recommended for pregnant/nursing women. Consult physician if taking medications (especially antidepressants), or have a medical condition.

May cause drowsiness and mild transient GI symptoms. Take with food in case of GI upset.

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

🧪 Formulation Notes

5-HTP is a naturally occurring amino acids that's a precursor for the neurotransmitter serotonin, which supports a positive mood and outlook and may help to manage appetite. NOW 5-HTP Sustained Release (Amino SR) Tablets allow for steady release and more gradual utilization of 5-HTP, and may be better tolerated by individuals who are sensitive to conventional 5-HTP supplement.

Non-GMO

Vegetarian/Vegan

Not manufactured with wheat, gluten, soy, corn, milk, egg, fish, shellfish or tree nut ingredients.

Additional Information

Sustained release - Amino SR Neurotransmitter Support Supports a Positive Mood

Non-GMO

Amino Acids Family owned since 1968.

This sustained release tablet is formulated to full release within 4 hours.

GMP Quality Assured

Product Details

UPC / SKU 7 33739 00115 3
DSLD Entry Date 2019-07-24
Product Type Amino acid/Protein
Form Tablet or Pill
Brand NOW
DSLD ID 204668
Data Updated 2026-04-11

Research Evidence

21 Research Sources
53 Avg Quality Score
11 Systematic Review
6 Rct
4 Meta Analysis
B Combination pharmacotherapy for the treatment of fibromyalgia in adults
Systematic Review The Cochrane database of systematic reviews 2018
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2001
B Tryptophan and 5-hydroxytryptophan for depression
Systematic Review The Cochrane database of systematic reviews 2002
B The impact of 5-hydroxytryptophan supplementation on sleep quality and gut microbiota composition in older adults: A randomized controlled trial
Rct Clinical nutrition (Edinburgh, Scotland) 2024
B The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
Rct Nutrients 2025
B The Efficacy of Different Triptans for the Treatment of Acute Headache in Pediatric Migraine: A Systematic Review
Systematic Review Indian pediatrics 2023
B The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis
Systematic Review Frontiers in pharmacology 2025
C Sleep disorders in children
Systematic Review BMJ clinical evidence 2010
C Effects of 5-hydroxytryptophan on distinct types of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2020
C Investigating genetic links between biological aging and adverse pregnancy outcomes
Meta Analysis Biogerontology 2025
View all evidence for 5 Htp →

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