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Skin

product on market Capsule Nutrafol Safety: 94/100
94/100

This product looks safe

  • Niacin: 150mg is 4.3× the Tolerable Upper Intake Level (35mg)
  • Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
  • 38% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The profile includes vitamins A, C, and D, which are supported by strong evidence for maintaining skin health and immune function. These nutrients contribute to cellular protection and collagen synthesis. However, the overall evidence coverage for this specific ingredient combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 150mg is 4.3× the Tolerable Upper Intake Level (35mg)

Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Skin
Open Full PDF View on NIH DSLD →
Details

Label Data

4 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
38%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
5 Calorie(s)
Total Carbohydrates
2 Gram(s) (1% DV)
Vitamin A
1000 mcg RAE (111% DV)
Vitamin C
40 mg (44% DV)
37.5 mcg (188% DV)
2.5× RDA — within safe limits 608 studies (A:16, B:251)
150 mg NE (938% DV)
Exceeds UL by 4.3× (UL: 35 mg) 196 studies (A:5, B:63)
680 mcg DFE (170% DV)
Exceeds UL by 680.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
20 mg (400% DV)
4.0× RDA — above typical dose 2 studies — no high-quality reviews
15 mg (136% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
200 mcg (364% DV)
3.6× RDA — above typical dose (UL: 0.4 mg) 173 studies (A:0, B:67)
Sodium
15 mg (1% DV)
Synergen Skin Complex (Patent Pending)
1 Gram(s)
Nutrafol Blend
425 mg

Other Ingredients

Hypromellose Rice Maltodextrin Rice Husk Pea Starch Pea Protein
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take four (4) capsules once daily with a meal. For best results, take for a minimum of 4-12 weeks and beyond.

Warnings & Precautions

Do not exceed recommended serving.

Caution: For adults only.

If you have a medical condition or are taking medications (especially blood thinning drugs), consult with your doctor before using. Do not use if pregnant or nursing.

Keep away from children.

Do not use if safety seal is damaged or missing.

Formulation Notes

Skin Wellness from within.

Physician-formulated to multi-target key root causes of mild to moderate acne in women using standardized vitamins, minerals, and natural ingredients that support skin health. With proprietary Synergen Skin Complex.

100% drug-free.

For non-cystic acne.

Does not contain: Gluten, soy, gelatin, artificial colors and flavoring.

100% Vegan.

Manufactured in the USA from domestic and imported ingredients.

Women

Clear skin nutraceutical

Additional Information

Store in a cool, dry place.

Check locally to recycle.

Metadata

Product Details

DSLD Entry Date2025-03-25
Product TypeOther Combinations
FormCapsule
BrandNutrafol
DSLD ID327462
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.