Skin by Nutrafol — Ingredients, Evidence & Safety

🟢 94/100

This product looks safe

Niacin: 150mg is 4.3× the Tolerable Upper Intake Level (35mg)
Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
38% of ingredients have research evidence

D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 150mg is 4.3× the Tolerable Upper Intake Level (35mg)

⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

4 Capsule(s) Serving Size

30 Servings

Other Combinations Product Type

38% Evidence Coverage

Supplement Facts — Evidence Check

Calories

5 Calorie(s)

Total Carbohydrates

2 Gram(s) (1% DV)

Vitamin A

1000 mcg RAE (111% DV)

Vitamin C

40 mg (44% DV)

Vitamin D

37.5 mcg (188% DV)

✅ 2.5× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.0375mg UL 0.1mg

Niacin

150 mg NE (938% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 4.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 150mg UL 35mg

Folate

680 mcg DFE (170% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 680mg UL 1.0mg

Pantothenic Acid

20 mg (400% DV)

📊 4.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 20mg

Zinc

15 mg (136% DV)

✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 15mg UL 40mg

Selenium

200 mcg (364% DV)

📊 3.6× RDA — above typical dose (UL: 0.4 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.2mg UL 0.4mg

Sodium

15 mg (1% DV)

Synergen Skin Complex (Patent Pending)

1 Gram(s)

Nutrafol Blend

425 mg

Other Ingredients

Hypromellose Rice Maltodextrin Rice Husk Pea Starch Pea Protein

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Vegan Vegetarian Women (not pregnant or lactating) Adult Female (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take four (4) capsules once daily with a meal. For best results, take for a minimum of 4-12 weeks and beyond.

⚠️ Warnings & Precautions

Do not exceed recommended serving.

Caution: For adults only.

If you have a medical condition or are taking medications (especially blood thinning drugs), consult with your doctor before using. Do not use if pregnant or nursing.

Keep away from children.

Do not use if safety seal is damaged or missing.

🧪 Formulation Notes

Skin Wellness from within.

Physician-formulated to multi-target key root causes of mild to moderate acne in women using standardized vitamins, minerals, and natural ingredients that support skin health. With proprietary Synergen Skin Complex.

100% drug-free.

For non-cystic acne.

Does not contain: Gluten, soy, gelatin, artificial colors and flavoring.

100% Vegan.

Manufactured in the USA from domestic and imported ingredients.

Women

Clear skin nutraceutical

Additional Information

Store in a cool, dry place.

Check locally to recycle.

Product Details

DSLD Entry Date 2025-03-25

Product Type Other Combinations

Form Capsule

Brand Nutrafol

DSLD ID 327462

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →