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Optimal Sleep II

product on market Capsule Seeking Health Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 80% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains B vitamins and magnesium, which support neurological function and relaxation. There is strong evidence that magnesium may improve sleep quality and duration. However, the overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Optimal Sleep II
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
30
Servings
Botanical with Nutrients
Product Type
80%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5 mg (417% DV)
4.2× RDA — above typical dose 76 studies (A:0, B:33)
5 mg (385% DV)
3.8× RDA — above typical dose 13 studies (A:0, B:1)
15 mg (94% DV)
1.1× RDA — within safe limits 196 studies (A:5, B:63)
5 mg (294% DV)
3.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
125 mg (30% DV)
Within RDA (0.3× RDA) 316 studies (A:8, B:159)
7 mg (64% DV)
Within RDA (0.6× RDA) 263 studies (A:6, B:134)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
125 mg
Market median: 450.0mg (502 products) 28 studies (A:0, B:8)
Market median: 100.0mg (108 products)
Lithium
2.5 mg

Other Ingredients

Hypromellose Water Ascorbyl Palmitate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: Take 2 capsules away from food 30 minutes prior to bedtime, or use as directed by your healthcare professional.

Warnings & Precautions

Children and pregnant or lactating women should consult their healthcare professional prior to use. Storage: Keep closed in a cool, dry place out of reach of children.

Children and pregnant or lactating women should consult their healthcare professional prior to use.

Do not use if tamper seal is damaged.

Formulation Notes

Optimal Sleep II supports healthy onset of sleep by helping to balance glutamate (a stimulating neurotransmitter) and GABA (a calming neurotransmitter.) This formula also supports the metabolism of serotonin, dopamine, norepinephrine, and epinephrine, as well as healthy evening cortisol levels. This product is intended to support occasional sleeplessness.

Does not contain: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, gluten, GMO, artificial colors, or artificial flavors.

Optimal Sleep II meets or exceeds cGMP Quality Standards.

Manufactured in the USA from globally sourced ingredients Third-party independently tested

Optimal Sleep II with B1, B2, Ornithine, and Lithium

Free of 5-HTP

Additional Information

Storage: Keep closed in a cool, dry place out of reach of children.

Find other effective health products at: www.seekinghealth.com This package is completely recyclable

Metadata

Product Details

UPC / SKU8 10007 52167 1
DSLD Entry Date2024-12-21
Product TypeBotanical with Nutrients
FormCapsule
BrandSeeking Health
DSLD ID322695
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.