Home/ Supplements/ Folate/ NR6

NR6

product on market Capsule Xtendlife Safety: 94/100
94/100

This product looks safe

  • Nicotinamide Riboside Chloride: 300mg is 8.6× the Tolerable Upper Intake Level (35mg)
  • 67% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

Nicotinamide riboside and resveratrol are studied for their roles in NAD+ production and cellular health, though clinical evidence remains moderate. Folate and vitamin B12 support methylation and neurological function with strong established evidence. Dimethylglycine HCl is included for metabolic support, though research on its efficacy is more limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Nicotinamide Riboside Chloride: 300mg is 8.6× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for NR6
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

150 mcg (37% DV)
Within RDA (0.4× RDA) 226 studies (A:10, B:105)
24 mcg (1000% DV)
10.0× RDA — above typical dose 139 studies (A:1, B:44)
Exceeds UL by 8.6× (UL: 35 mg) 196 studies (A:5, B:63)
Dimethylglycine HCl
100 mg
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)
Piperine
10 mg

Other Ingredients

Hydroxypropylmethyl Cellulose Water
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions For Use Adults: Take 1 capsule per day.

Formulation Notes

Xtend-Life NR6 includes a synergistic combination of ingredients to support optimal cellular energy.

Cellular Energy Support

Additional Information

Store in a cool, dry place.

Best Quality Guarantee

NewZealand.com Licence No.100055

USA/Canada Ph: 1888 487 9304

Metadata

Product Details

UPC / SKU9 421904 523425
DSLD Entry Date2024-09-25
Product TypeOther Combinations
FormCapsule
BrandXtendlife
DSLD ID318037
Data Updated2026-04-11
Research

Research Evidence

363
Research Sources
57
Avg Quality
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A Homocysteine-lowering interventions for preventing cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
Meta Analysis Digestive diseases and sciences 2021 PubMed DOI
A The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
Meta Analysis Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 2021 PubMed DOI
A A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Meta Analysis Nutrients 2024 PubMed DOI
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025 PubMed DOI
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019 PubMed DOI
A Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2022 PubMed DOI
A Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
Meta Analysis Critical reviews in food science and nutrition 2023 PubMed DOI
A Digital tracking, provider decision support systems, and targeted client communication via mobile devices to improve primary health care
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
View all evidence for Folate →
Compare

Similar Products

Bio-Plus Biotin With Folic Acid
Douglas Laboratories · Capsule
100
Folic Acid
OL Olympian Labs · Capsule
100
L-5-MTHF Natural S-Isomer
Designs for Health · Capsule
100
Folic Acid
DaVinci Laboratories Of Vermont · Capsule
100
SAMe with Vitamins B-6, B-12 and 5-MTHF
Designs for Health · Capsule
100
View all Folate products →
Folate research Best Folate All Folate products More from Xtendlife View on NIH DSLD →

This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.