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JointFlex+

product on market Capsule Herbs SRA Safety: 96/100
96/100

This product looks safe

  • Vitamin D3: 5mg is 50.0× the Tolerable Upper Intake Level (0.1mg)
  • 60% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains glucosamine, chondroitin, and collagen, which are commonly used to support joint cartilage and lubrication. Research provides moderate evidence that these ingredients may help manage joint discomfort. However, the overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Vitamin D3: 5mg is 50.0× the Tolerable Upper Intake Level (0.1mg)

Label

Product Label

Label for JointFlex+
Open Full PDF View on NIH DSLD →
Details

Label Data

500 mg
Serving Size
60
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
85 mg
Market median: 600.0mg (79 products) 25 studies (A:0, B:6)
Shark Cartilage
80 mg
Market median: 100.0mg (173 products)
Market median: 20.0mg (931 products) 234 studies (A:1, B:90)
Market median: 1000.0mg (2 products)
Vitamin C
40 mg
25 mg
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
20 mg
1.8× RDA — within safe limits 263 studies (A:6, B:134)
5 mg
Exceeds UL by 50.0× (UL: 0.1 mg) 608 studies (A:16, B:251)

Other Ingredients

Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, take two (2) capsules twice daily. For best result, take capsules in the morning and in the afternoon with 8 oz of water.

Warnings & Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18 and individuals with a known medical condition should consult a physician before using this or any dietary supplement. Keep out of reach of children.

Do not use if safety seal is damaged or missing.

Allergen Information: Contains shellfish, Fish (Shark).

Formulation Notes

Promotes cartilage and joint health Increases mobility and flexibility

Additional Information

Store in a cool, dry place.

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Metadata

Product Details

DSLD Entry Date2024-06-20
Product TypeOther Combinations
FormCapsule
DSLD ID316178
Data Updated2026-04-11
Research

Research Evidence

39
Research Sources
50
Avg Quality
20
Rct
9
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Regulatory Source
1
Openfda Safety
B Interventions for the management of temporomandibular joint osteoarthritis
Systematic Review The Cochrane database of systematic reviews 2012 PubMed DOI
B Glucosamine therapy for treating osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2005 PubMed
B Chondroitin for osteoarthritis
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
B Efficacy and safety of the combination of glucosamine and chondroitin for knee osteoarthritis: a systematic review and meta-analysis
Meta Analysis Archives of orthopaedic and trauma surgery 2023 PubMed DOI
B Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Rct The New England journal of medicine 2006 PubMed
B Oral Glucosamine in the Treatment of Temporomandibular Joint Osteoarthritis: A Systematic Review
Systematic Review International journal of molecular sciences 2023 PubMed DOI
B Scientific Opinion on glucosamine and joint health
Regulatory Source EFSA Journal 2009 DOI
B Clinical Efficacy and Safety of Chondroitin Combined with Glucosamine in the Treatment of Knee Osteoarthritis: A Systematic Review and Meta-Analysis
Meta Analysis Computational and mathematical methods in medicine 2022 PubMed DOI
B Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib
Rct Annals of the rheumatic diseases 2016 PubMed DOI
B Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials
Meta Analysis Journal of orthopaedic surgery and research 2018 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.