NMN Plus by Esmond Natural — Ingredients, Evidence & Safety

Product Label

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Safety Alerts

⚠️ Nicotinamide Riboside Chloride: 320mg is 9.1× the Tolerable Upper Intake Level (35mg)

Label Data

2 Capsule(s) Serving Size

30 Servings

Non-Nutrient/Non-Botanical Product Type

75% Evidence Coverage

Supplement Facts — Evidence Check

Nicotinamide Riboside Chloride

320 mg

⚠️ Exceeds Tolerable Upper Intake Level by 9.1× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 320mg UL 35mg

Quercetin

250 mg

📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)

This product: 250mg

Trans-Resveratrol

150 mg

📊 Market median: 167.0mg (311 products) 📚 182 studies (Tier A: 0, B: 65)

This product: 150mg

Betaine Anhydrous

50 mg

📊 Market median: 496.0mg (192 products) 📚 20 studies — no high-quality reviews

This product: 50mg

Other Ingredients

Gelatin Dicalcium Phosphate Silica Magnesium Stearate

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (100% of products) Structure/Function (90% of products) Nutrient (28% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: For adults, take two (2) capsules daily or as recommended by your healthcare professional. As a reminder, discuss the supplements and medications you take with your health care providers.

⚠️ Warnings & Precautions

Warning: If you are pregnant, nursing or taking any medications, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Store in a dry place and avoid excessive heat. Tamper resistant: Do not use if imprinted seal under cap is broken or missing.

🧪 Formulation Notes

Nicotinamide Mononucleotide (NMN) has an important effect on the production of cellular energy and as the precursor to NAD+ NMN is a naturally occurring form of Vitamin B3 in our body and can also be found in fruits and vegetables. When it comes to the production of NAD+, NMN plays an important role. Supplementation with NMN promotes positive effect on health, longevity and significantly improves quality of life as you age.

NMN Plus NMN9600 with Quercetin Trans-Resveratrol - Betaine Anhydrous

Supports healthy aging & NAD+ production; supports energy production

Additional Information

Esmondnatural Integrated health

Store in a dry place and avoid excessive heat.

Elite Series Herbal Health Since 1994

GMP

Product Details

UPC / SKU 6 41399 08838 7

DSLD Entry Date 2024-07-25

Product Type Non-Nutrient/Non-Botanical

Form Capsule

Brand Esmond Natural

DSLD ID 315909

Data Updated 2026-04-11

Research Evidence

10 Research Sources

49 Avg Quality Score

8 Rct

1 Systematic Review

1 Clinical Trial

B Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults

Rct Nature communications 2018

PubMed DOI

C The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials

Systematic Review Frontiers in nutrition 2023

PubMed DOI

C Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial.

Rct Nature aging

PubMed DOI

C Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults

Rct Scientific reports 2019

PubMed DOI

C Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

Rct Cell reports 2019

PubMed DOI

C Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin

Rct Aging cell 2023

PubMed DOI

C Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI

Rct BMC nephrology 2020

PubMed DOI

C Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19

Clinical Trial ClinicalTrials.gov 2021

ClinicalTrials.gov

C A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals.

Rct JCI insight

PubMed DOI

C Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double-Blind Randomized Crossover Placebo-Controlled Trial.

Rct Aging cell

PubMed DOI

View all evidence for Nicotinamide Riboside →