🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

1 Vegetarian Capsule(s) Serving Size
Vitamin Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

125 mg
📊 Market median: 300.0mg (26 products) 📚 7 studies (Tier A: 0, B: 1)
This product: 125mg

Other Ingredients

Microcrystalline Cellulose Vegetarian Capsule Farm Fresh Factors Magnesium Stearate Stearic Acid

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (100% of products) Structure/Function (90% of products) Nutrient (28% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Suggested usage: 1 capsule 1-2 times per day or as directed by a health professional.

⚠️ Warnings & Precautions

Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding, or trying to conceive, or if you are taking medication, have a medical condition, or anticipate surgery.

Keep out of the reach of children.

Sealed for your protection. Do not use if seal is broken.

🧪 Formulation Notes

Nicotinamide riboside is the metabolically active form of niacin. As a precursor to the coenzymated form nicotinamide adenine dinucleotide (NAD+), nicotinamide riboside has been shown to significantly increase NAD+ levels. NAD+ is essential for mitochondrial health and function as well as healthy cellular metabolism and healthy aging. In addition, taking nicotinamide riboside does not cause undesirable flushing associated with niacin. Nicotinamide riboside truly is the next generation vitamin B3!

Contains no artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs.

Suitable for vegetarians/vegans.

B3

Additional Information

isura Non-GMO Mass Spec Documentation Lab Tested

Manufactured by Natural Factors to ensure safety and potency in accordance with Good Manufacturing Practices (GMP) of the FDA and Health Canada.

For freshness, store in a cool, dry place.

Product of Canada Purity & Potency Guaranteed Recyclable container and label.

The most metabolically active form

R0

This product has passed the most rigorous testing in the world for contaminants and quality. isura.com

What does coenzymated mean? In order for B vitamins to be utilized effectively by the body, they must be converted into their metabolically active coenzyme forms. For example, the coenzyme form of niacin is NAD+. A coenzyme is a naturally occurring compound that partners with specific enzymes in order to help promote a number of beneficial metabolic reactions in the body. Without the coenzyme, the enzyme cannot promote the biochemical reaction that is responsible for our survival. This dual cooperation between coenzyme and enzyme is a process called coenzymated. Taking B vitamins already in their coenzymated forms allows the body to use them directly. Thus, the amount that is needed by the body is less in order to achieve the same benefits. Biocoenzymated takes it one step further.

The synergy between the phytochemicals found in these plant extracts and the coenzyme B vitamin optimizes absorption. The results? Biocoenzymated delivers the most metabolically active nutrients to your cells to utilize most effectively. Feel the difference.

Product Details

UPC / SKU 0 68958 01254 4
DSLD Entry Date 2018-09-21
Product Type Vitamin
Form Capsule
DSLD ID 180925
Data Updated 2026-04-11

Research Evidence

10 Research Sources
49 Avg Quality Score
8 Rct
1 Systematic Review
1 Clinical Trial
B Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Rct Nature communications 2018
C The effects of NAD+ precursor (nicotinic acid and nicotinamide) supplementation on weight loss and related hormones: a systematic review and meta-regression analysis of randomized controlled trials
Systematic Review Frontiers in nutrition 2023
C Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial.
Rct Nature aging
C Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults
Rct Scientific reports 2019
C Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures
Rct Cell reports 2019
C Oral nicotinamide riboside raises NAD+ and lowers biomarkers of neurodegenerative pathology in plasma extracellular vesicles enriched for neuronal origin
Rct Aging cell 2023
C Nicotinamide riboside with pterostilbene (NRPT) increases NAD+ in patients with acute kidney injury (AKI): a randomized, double-blind, placebo-controlled, stepwise safety study of escalating doses of NRPT in patients with AKI
Rct BMC nephrology 2020
C Clinical Trial of Niagen to Examine Recovery in People With Persistent Cognitive and Physical Symptoms After COVID-19
Clinical Trial ClinicalTrials.gov 2021
C A randomized placebo-controlled trial of nicotinamide riboside and pterostilbene supplementation in experimental muscle injury in elderly individuals.
Rct JCI insight
C Nicotinamide Riboside Supplementation Benefits in Patients With Werner Syndrome: A Double-Blind Randomized Crossover Placebo-Controlled Trial.
Rct Aging cell
View all evidence for Nicotinamide Riboside →

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