Focus Now

product on market Capsule Rise-N-Shine 🟢 Safety: 86/100
Brand: Rise-N-Shine
🟢 86/100

This product is generally safe

  • Folate: 670mg is 670.0× the Tolerable Upper Intake Level (1.0mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 80% of ingredients have research evidence
C Label Compliance Grade

Product Label

Label for Focus Now
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Safety Alerts

⚠️ Folate: 670mg is 670.0× the Tolerable Upper Intake Level (1.0mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
80% Evidence Coverage

Supplement Facts — Evidence Check

1.5 mg (125% DV)
✅ 1.2× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 1.5mg
1.7 mg (131% DV)
✅ 1.3× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 1.7mg
30 mg (188% DV)
✅ 2.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 30mg UL 35mg
40 mg (2353% DV)
📊 30.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 40mg UL 100mg
670 mcg DFE (167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 670.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 670mg UL 1.0mg
500 mcg (20833% DV)
📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.5mg
100 mcg (333% DV)
📊 3.3× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.1mg
10 mg (200% DV)
✅ 2.0× RDA — within safe limits 📚 1 studies — no high-quality reviews
RDA 5mg This product: 10mg
100 mg (24% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 100mg
Proprietary Blend
330 mg

Other Ingredients

Rice Flour Bovine Gelatin Magnesium Stearate

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Suggested use: 1 capsule, taken 1 to 2 times daily with meals or as directed by a healthcare professional. This product should be used in conjunction with a sensible diet and exercise program.

⚠️ Warnings & Precautions

Caution: As with any dietary supplement, check with your physician before taking this product. Do not exceed recommended dose. Notice: Most people should not experience "niacin skin flush" when using this product. However a few sensitive individuals may experience some flushing. Do not take on an empty stomach. Do not use if safety seal is damaged or missing. Warning: This product contains 100 mg of caffeine per serving (equivalent to approximately 1 cup of coffee).

This product is manufactured and packaged in a facility which may also process milk, soy, wheat, egg, peanuts, tree nuts, fish and crustacean shellfish.

Keep out of reach of children.

🧪 Formulation Notes

Contains natural and synthetic/artificial ingredients.

Premium concentration formula

Results may vary.

Additional Information

Store in a cool, dry place

Formulated in the USA

GMP Quality Good Manufacturing Practice Certification

Product Details

UPC / SKU 8 50046 24408 7
DSLD Entry Date 2024-05-23
Product Type Other Combinations
Form Capsule
Brand Rise-N-Shine
DSLD ID 313441
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
PubMed Cochrane
View all evidence for Thiamine →

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