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Turn Down

product on market Powder Isotonix Essentials Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 36% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The profile contains essential vitamins A, C, and D3, which are supported by strong evidence for maintaining immune function and bone health. These nutrients act as antioxidants and regulators of cellular processes. Due to the low evidence coverage, the specific synergistic effects of this combination remain limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Turn Down
Open Full PDF View on NIH DSLD →
Details

Label Data

13.3 Gram(s)
Serving Size
30
Servings
Other Combinations
Product Type
36%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
20 Calorie(s)
Total Carbohydrates
5 Gram(s) (2% DV)
Vitamin A
360 mcg RAE (40% DV)
Vitamin C
600 mg (667% DV)
12.5 mcg (63% DV)
Within RDA (0.8× RDA) 608 studies (A:16, B:251)
2.88 mg (222% DV)
2.2× RDA — within safe limits 13 studies (A:0, B:1)
20 mg (125% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
4 mg (235% DV)
3.1× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
Calcium
375 mg (29% DV)
300 mg (71% DV)
Within RDA (0.7× RDA) 316 studies (A:8, B:159)
0.5 mg (22% DV)
Within RDA (0.2× RDA) 9 studies — no high-quality reviews
Potassium
380 mg (8% DV)
500 mg
Market median: 500.0mg (70 products)
0.5 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Fructose Citric Acid Orange Juice, Powder Malic Acid Glucose Orange Flavor, Natural Maltodextrin Silicon Dioxide Rebaudioside A Luo Han Guo fruit extract Mango Flavor, Natural Passionfruit Flavor, Natural Sodium Bicarbonate natural French Vanilla
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions for use 1 Pour contents of packet into a cup 2 Add 8 fl oz of water into the cup and stir As a dietary supplement, take once daily or as directed by your healthcare provider. Maximum absorption occurs when taken on an empty stomach. This product is isotonic only if the specified amount of water and powder are used.

Warnings & Precautions

Warning: Magnesium should be used cautiously in individuals with reduced kidney function due to an increased risk of hypermagnesemia. Discontinue use and consult your healthcare provider if you experience diarrhea, abdominal cramping or discomfort. Do not use if packet has been opened.

If you are taking any other sleep aid, monoamine oxidase inhibitors (MAOI) or other antidepressants such as Zoloft or Paxil, psychoactive or tranquilizing drugs such as Klonopin or Valium, or pain medications such as Demerol or Ultram, consult your healthcare provider before using this product. Take this supplement separately from prescription drugs. If you are currently using any other prescription drugs or have an ongoing medical condition, consult your healthcare provider before using this product. If you are pregnant or breastfeeding, do not use this product.

Keep out of reach of children.

Formulation Notes

A custom formula designed for relaxation. Features a dynamic blend of vitamins, amino acids and minerals.

This product contains no added wheat, soy, yeast, gluten, artificial flavor, salt, preservatives or milk.

Gluten free

Mood sleep & calmness Want to be stress free? Do you dream of a better night's sleep. Isotonix Essentials Turn Down is a custom formula designed for people who need a dose of relaxation. Whether you are an on-the-go traveler a busy parent or hardworking college student, everyone needs to Turn Down from time to time. Our Turn Down formula helps enhance and stabilize your mood, promotes mental clarity and supports a healthy sleep quality.

Additional Information

Store in a cool, dry, place.

30 - 0.47 oz (13.3 g) packets

Metadata

Product Details

DSLD Entry Date2024-07-25
Product TypeOther Combinations
FormPowder
BrandIsotonix Essentials
DSLD ID313419
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.