100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 38% of ingredients have research evidence
A
Label Compliance Grade
What the Evidence Says
✨ AI-generated · Qwen 3.6
· methodology
This formula contains milk thistle and artichoke extract, which have moderate evidence for supporting liver function and bile flow. Curcumin and choline contribute antioxidant and lipid metabolism support, though overall evidence coverage for this specific combination is limited. The ingredient profile maintains a high safety score.
AI-generated summary based on research evidence. Not medical advice.
Details
Label Data
2 Capsule(s)
Serving Size
Other Combinations
Product Type
Ingredients
Supplement Facts — Evidence Check
Within RDA (0.1× RDA)
38 studies (A:1, B:7)
Market median: 300.0mg (159 products)
Market median: 450.0mg (254 products)
243 studies (A:0, B:100)
Market median: 250.0mg (562 products)
55 studies (A:0, B:19)
Market median: 650.0mg (87 products)
1 studies — no high-quality reviews
Rehmannia Root Extract, Powder
80 mg
Market median: 500.0mg (193 products)
7 studies — no high-quality reviews
Other Ingredients
Cellulose
Magnesium Silicate
Silica
Ascorbyl Palmitate
Cellulose
Claims
Label Claims — Verification
Unverified
All Other
Unverified
Structure/Function
Info
Product Information
Directions for Use
Recommendations: Take 2 capsules 1-2 times daily, or as directed by your healthcare professional.
Warnings & Precautions
Keep out of reach of children
Use only if safety seal is intact
Warning: If pregnant, consult your physician before taking.
Formulation Notes
Excludes coatings, binders, gluten (wheat, rye, barley), milk/dairy (casein, whey), soy protein, egg protein, sugar.
Verified by independent testing
Raw materials and finished products are independently tested by U.S. labs.
Additional Information
Store sealed in a cool dry place
Learn more at vitalnutrients.net
Metadata
Product Details
UPC / SKU6 93465 23511 9
DSLD Entry Date2024-12-21
Product TypeOther Combinations
FormCapsule
Data Updated2026-04-11
Research
Research Evidence
B
Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis
Biological psychiatry. Cognitive neuroscience and neuroimaging
2024
PubMed
DOI
B
Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline
Briefings in bioinformatics
2026
PubMed
DOI
B
Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline
Journal of gastroenterology
2022
PubMed
DOI
B
Scientific Opinion on health claims related to choline
Regulatory Source
EFSA Journal
2011
DOI
C
Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis
Nutrition reviews
2022
PubMed
DOI
C
Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review
Psychotherapy and psychosomatics
2013
PubMed
DOI
C
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct
The British journal of nutrition
2007
PubMed
C
Differential metabolism of choline supplements in adult volunteers.
View all evidence for Choline →
This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.
