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Activated B-Complex

product on market Powder Isotonix Safety: 97/100
97/100

This product looks safe

  • Folate: 430mg is 430.0× the Tolerable Upper Intake Level (1.0mg)
  • 64% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins including thiamine, riboflavin, and niacin, which are essential for cellular energy metabolism and neurological function. There is strong clinical evidence supporting the role of these nutrients in maintaining metabolic health. The ingredient profile is associated with a high safety score, indicating a low risk of adverse effects.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 430mg is 430.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Activated B-Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

3.3 Gram(s)
Serving Size
90
Servings
Other Combinations
Product Type
64%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Carbohydrates
2 Gram(s) (1% DV)
2 mg (167% DV)
1.7× RDA — within safe limits 76 studies (A:0, B:33)
3 mg (231% DV)
2.3× RDA — within safe limits 13 studies (A:0, B:1)
20 mg NE (125% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
6 mg (353% DV)
4.6× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
430 mcg DFE (108% DV)
Exceeds UL by 430.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
120 mcg (5000% DV)
50.0× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
20 mg (400% DV)
4.0× RDA — above typical dose 2 studies — no high-quality reviews
Potassium
95 mg (2% DV)

Other Ingredients

Fructose Glucose Citric Acid Maltodextrin Silicon Dioxide Apple Fiber Apple Pectin Lemon Flavor Stearic Acid Calcium Sulfate Lime flavor
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions for use: Pour 1 level, white bottle capful of powder into the overcap. Add water to the line on the overcap (2 fl oz/60 ml) and stir. As a dietary supplement, take once daily or as directed by your healthcare provider. Maximum absorption occurs when taken on an empty stomach. This product is Isotonic only if the specified amounts of powder and water are used.

Warnings & Precautions

Warning: If you are currently using prescription drugs, have an ongoing medical condition or are pregnant or breastfeeding, consult your healthcare provider before using this product.

Keep out of the reach of children.

Do not use if safety seal is broken or missing.

Resale on third-party websites is strictly prohibited unless specifically authorized by Market America or its corporate affiliates. If barcodes are altered or you purchase this product from an unauthorized third-party website, the product is not guaranteed by Market America or its corporate affiliates.

Formulation Notes

Increases energy Promotes a healthy nervous system, bone marrow and intestinal tract Promotes cardiovascular health May help decrease stress and improve mood

This vegan product contains no added wheat, soy, yeast, gluten, artificial flavor, starch, salt, preservatives or milk.

Vegan

Gluten free

Additional Information

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU8 48570 00113 9
DSLD Entry Date2023-11-22
Product TypeOther Combinations
FormPowder
DSLD ID298757
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.