Vitamin B Complex by New Chapter — Ingredients, Evidence & Safety

🟢 96/100

This product looks safe

Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
78% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size

60 Servings

Botanical with Nutrients Product Type

78% Evidence Coverage

Supplement Facts — Evidence Check

Thiamin

1.2 mg (100% DV)

✅ Within RDA (1.0× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 1.2mg

Riboflavin

1.3 mg (100% DV)

✅ Within RDA (1.0× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 1.3mg

Niacin

16 mg (100% DV)

✅ 1.1× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 16mg UL 35mg

Vitamin B6

3.4 mg (200% DV)

✅ 2.6× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 3.4mg UL 100mg

Folate

400 mcg DFE (100% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 400.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 400mg UL 1.0mg

Vitamin B12

12 mcg (500% DV)

📊 5.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.012mg

Biotin

30 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.03mg

Pantothenic Acid

5 mg (100% DV)

✅ Within RDA (1.0× RDA of 5 mg) 📚 1 studies — no high-quality reviews

RDA 5mg This product: 5mg

Energy and Digestion Support Blend

75 mg

Other Ingredients

organic Gum Acacia organic Brown Rice Silica Soy Flour Saccharomyces cerevisiae Orange, Powder Papain Bromelain Lactic Acid Bacteria Silica organic Coating

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Kosher Organic Gluten Free

Product Information

📋 Directions for Use

Suggested use: One tablet daily. Can be taken anytime, even on an empty stomach.

⚠️ Warnings & Precautions

Caution: As with any dietary supplement, advise your healthcare professional of the use of this product if you have a medical condition or are taking medication. If you are nursing, pregnant, or considering pregnancy, you should consult your healthcare professional prior to using this product.

Keep out of reach of children.

Contains: Fermented soy.

🧪 Formulation Notes

Certified gluten-free by NSF; 100% Vegan; No artificial flavors or colors.

With Folate for immune support

Fermented for absorption Nutrition crafted for: Immune, energy, beauty & brain support

The magic inside: Whole-food B Vitamins with herbs

USDA Organic

Non GMO Project Verified nongmoproject.org Certified NSF Gluten-free

OU (Kosher)

Certified Organic by International Certification Services, Inc., Medina, ND, USA

Manufactured in the US from globally sourced ingredients

Additional Information

Please refer to newchapter.com for more information about this product and its benefits.

The New Chapter Money-Back Guarantee We proudly stand behind every product we make. However, if you are not satisfied, please visit www.newchapter.com/guarantee for refund details. Please recycle this bottle after use.

USDA Organic Non GMO Project Verified nongmoproject.org NSF Certified Gluten-free OU (Kosher)

Product Details

UPC / SKU 7 27783 90261 0

DSLD Entry Date 2023-07-18

Product Type Botanical with Nutrients

Form Tablet or Pill

Brand New Chapter

DSLD ID 294172

Data Updated 2026-04-11

Research Evidence

100 Research Sources

56 Avg Quality Score

48 Systematic Review

30 Meta Analysis

13 Rct

6 Clinical Trial

1 Cochrane Review

1 Regulatory Source

B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol

Systematic Review The Cochrane database of systematic reviews 2013

PubMed DOI Cochrane

B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials

Systematic Review Nutritional neuroscience 2023

PubMed DOI

B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis

Meta Analysis BMJ open 2022

PubMed DOI

B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024

PubMed DOI

B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis

Systematic Review Intensive care medicine 2022

PubMed DOI

B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis

Meta Analysis Pain medicine (Malden, Mass.) 2020

PubMed DOI

B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis

Meta Analysis Critical care medicine 2021

PubMed DOI

B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2022

PubMed DOI

B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis

Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023

PubMed DOI

B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse

Systematic Review The Cochrane database of systematic reviews 2004

PubMed Cochrane

View all evidence for Thiamine →