🟢 96/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 33% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label Data

2 Capsule(s) Serving Size
40 Servings
Other Combinations Product Type
33% Evidence Coverage

Supplement Facts — Evidence Check

Calories
5 {Calories}
Total Carbohydrates
1 g (1% DV)
50 mg (250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
380 mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 380mg
Yucca Root
300 mg
200 mg
📊 Market median: 200.0mg (136 products) 📚 3 studies — no high-quality reviews
This product: 200mg
100 mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 100mg
40 mg
📊 Market median: 380.0mg (120 products) 📚 8 studies — no high-quality reviews
This product: 40mg
Cayenne Pepper
20 mg

Other Ingredients

Gelatin capsule shell May include

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take two to four capsules daily.

⚠️ Warnings & Precautions

Keep out of the reach of children.

Do not purchase if seal is broken.

Contains ingredients derived from shrimp and crab shell.

🧪 Formulation Notes

JointAssure was formulated to help nutritionally support cartilage and joints with Glucosamine Sulfate. JointAssure also contains other high-quality ingredients such as Yucca, Bromelain, Curcumin, Feverfew, and Niacin.

Contains ingredients derived from shrimp and crab shell.

This product contains no added sugar, yeast, corn, milk, soy, starch, or artificial colors, flavors and preservatives.

Additional Information

Store in a cool, dry place.

Please recycle this bottle when empty.

Product Details

UPC / SKU 7 88111 00021 7
DSLD Entry Date 2011-12-23
Product Type Other Combinations
Form Capsule
DSLD ID 2927
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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