Methyl-Guard Plus
92/100
This product looks safe
- Folate: 5mg is 5.0× the Tolerable Upper Intake Level (1.0mg)
- 80% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Folate: 5mg is 5.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
1 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
80%
Evidence Coverage
Supplement Facts — Evidence Check
90 mg
(6923% DV)
📊 69.2× RDA — above typical dose
📚 12 studies (Tier A: 0, B: 1)
45 mg
(2647% DV)
📊 34.6× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
5 mcg DFE
(1250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 5.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
3 mg
(125000% DV)
📊 1250.0× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
1.8 Gram(s)
📊 Market median: 496.0mg (192 products)
📚 20 studies — no high-quality reviews
Other Ingredients
Hypromellose (derived from Cellulose) Capsule
Calcium Citrate
Calcium Laurate
Label Claims — Verification
❓
Nutrient
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (85% of products)
Nutrient (48% of products)
No Claim (1% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
Suggested use: Take 1-3 capsules daily or as recommended by your health-care practitioner.
⚠️ Warnings & Precautions
Tamper evident: Use only of bottle is sealed.
If pregnant, consult your health-care practitioner before using this product.
🧪 Formulation Notes
Heart/vessels Mood
Gluten free
Methylation factors
This product uses Gnosis S.p.A.'s L-5-methyltetrahydrofolic acid, glucosamine salt (quatrefolic).
Additional Information
Store tightly sealed in a cool, dry place.
Manufactured in the USA using US & imported ingredients
Product Details
Research Evidence
22
Research Sources
49
Avg Quality Score
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B
Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
B
Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
B
Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
B
Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
C
Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
C
The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
C
Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
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