🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

2 Chewable Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Calories
20 Calorie(s) (1% DV)
Total Carbohydrates
4 Gram(s) (1% DV)
Vitamin C
500 mg (840% DV)
400 IU (1340% DV)
📊 17.9× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 268.0mg UL 1000mg
25 mg (170% DV)
✅ 2.3× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 25mg UL 40mg
2 mg (100% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
10 mg
📊 Market median: 10.0mg (105 products) 📚 1 studies (Tier A: 0, B: 1)
This product: 10mg
2 mg
📊 Market median: 4.0mg (32 products)
This product: 2mg

Other Ingredients

Dextrose D-Mannitol Bilberry fruit extract Natural Flavors Stearic Acid Strawberry flavor Raspberry flavor Citric Acid Blueberry flavor Calcium Silicate Silicon Dioxide Sucralose Maltodextrin Gum Acacia Vegetable Juice

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

2 chewables per day

Suggested Adult Intake: 2 chewable tablets per day with a meal, or as directed by your physician.

⚠️ Warnings & Precautions

Contains: Milk, fish (cod, pollack, haddock, hake, cusk, redfish, sole, flounder).

Warnings: Do not use if safety seal under cap is broken or missing.

Do not use this product if you are allergic to milk or fish.

If you are taking prescription medications or are being treated for a medical condition, you should consult your healthcare professional before taking this (or any) dietary supplement.

Keep out of reach of children.

Higher levels of Zinc may cause an upset stomach. Systane ICaps AREDS2 Formula contains only 25 mg of Zinc to minimize negative side effects without impacting performance.

🧪 Formulation Notes

Age-related eye disease study 2 Contains ingredients clinically shown to support eye health in people with intermediate to advanced age-related macular degeneration (AMD)

No added beta-carotene.

Includes Lutein and Zeaxanthin.

Contains ingredients used in the Age-related Eye Disease Study 2 (AREDS2) conducted by the National Eye Institute to support eye heath in people with Age-related macular degeneration (AMD)

Country of Origin: Canada

Nutrient Ingredient levels tested in the age-related eye disease study 2 Systane ICaps AREDS2 softgel amount per day Vitamin C 500 mg Vitamin E 400 IU Zinc 25 mg Copper 2 mg Lutein 10 mg Zeaxanthin 2 mg The AREDS2 clinical study tested 80 mg and 25 mg of Zinc. Results reveled a formulation containing 25 mg Zinc provided the same protective effect against developing advanced AMD.

Additional Information

Easy open cap

Store container at room temperature with the lid tightly closed.

Questions or comments? Call us. 1 (800) 757-9195

Product Details

UPC / SKU 3 00658 04803 5
DSLD Entry Date 2022-06-16
Product Type Other Combinations
Form Tablet or Pill
Brand Alcon
DSLD ID 270319
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
View all evidence for Vitamin C →

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