B Complex by Innate Response Formulas — Ingredients, Evidence & Safety

🟢 92/100

This product looks safe

Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)
Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
78% of ingredients have research evidence

D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)

⚠️ Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size

180 Servings

Botanical with Nutrients Product Type

78% Evidence Coverage

Supplement Facts — Evidence Check

Thiamine

9 mg (750% DV)

📊 7.5× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 9mg

Riboflavin

9 mg (692% DV)

📊 6.9× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 9mg

Niacin

45 mg (281% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 45mg UL 35mg

Vitamin B6

10 mg (588% DV)

📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 10mg UL 100mg

Folate

400 mcg DFE (100% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 400.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 400mg UL 1.0mg

Vitamin B12

50 mcg (2083% DV)

📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.05mg

Biotin

30 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.03mg

Pantothenic Acid

45 mg (900% DV)

📊 9.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 45mg

Kale

125 mg

Other Ingredients

Cellulose Silica Stearic Acid

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Kosher Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Use: 1 tablet daily, or as directed by your healthcare practitioner. May be taken anytime throughout the day, even on an empty stomach.

🧪 Formulation Notes

Promotes healthy energy levels

Non GMO Project Verified nongmoproject.org Glyphosate Residue Free detoxproject.org Tested Gluten Free Dairy Free Soy free

Vegan

Kosher

In this INNATE Response product each vitamin or mineral is paired with an ideal whole food using our unique process to deliver guaranteed potency and the benefit of health-promoting compounds present in the whole food itself.

Additional Information

Please Recycle Vis medicatrix naturae

To learn more about our seals, please visit innateresponse.com/standards.

Certified B Corporation Non GMO Project Verified nongmoproject.org Glyphosate Residue Free detoxproject.org Tested 125+ pesticides & herbicides Tested Gluten Free Certified Vegan Vegan.org OK (Kosher)

At INNATE Response we share your belief that nothing is more important than supporting your body's innate ability to heal. To that end, we develop nutrient-rich supplements.

See how they're made at innateresponse.com/showme. Satisfaction guaranteed or your money back. Learn more at: www.innateresponse.com

Product Details

UPC / SKU 0 51494 40012 8

DSLD Entry Date 2022-06-16

Product Type Botanical with Nutrients

Form Tablet or Pill

Brand Innate Response Formulas

DSLD ID 267842

Data Updated 2026-04-11

Research Evidence

100 Research Sources

56 Avg Quality Score

48 Systematic Review

30 Meta Analysis

13 Rct

6 Clinical Trial

1 Cochrane Review

1 Regulatory Source

B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol

Systematic Review The Cochrane database of systematic reviews 2013

PubMed DOI Cochrane

B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials

Systematic Review Nutritional neuroscience 2023

PubMed DOI

B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis

Meta Analysis BMJ open 2022

PubMed DOI

B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024

PubMed DOI

B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis

Systematic Review Intensive care medicine 2022

PubMed DOI

B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis

Meta Analysis Pain medicine (Malden, Mass.) 2020

PubMed DOI

B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis

Meta Analysis Critical care medicine 2021

PubMed DOI

B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2022

PubMed DOI

B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis

Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023

PubMed DOI

B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse

Systematic Review The Cochrane database of systematic reviews 2004

PubMed Cochrane

View all evidence for Thiamine →