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B Complex

product on market Tablet or Pill Innate Response Formulas Safety: 92/100
92/100

This product looks safe

  • Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)
  • Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
  • 78% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The B-complex vitamins, including thiamine, riboflavin, and folate, are essential for energy metabolism and neurological function. Strong research evidence supports their role in cellular energy production and cognitive health. This profile maintains a high safety score, indicating a low risk of adverse effects for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)

Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for B Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
180
Servings
Botanical with Nutrients
Product Type
78%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

9 mg (750% DV)
7.5× RDA — above typical dose 76 studies (A:0, B:33)
9 mg (692% DV)
6.9× RDA — above typical dose 13 studies (A:0, B:1)
45 mg (281% DV)
Exceeds UL by 1.3× (UL: 35 mg) 196 studies (A:5, B:63)
10 mg (588% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg DFE (100% DV)
Exceeds UL by 400.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
50 mcg (2083% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
30 mcg (100% DV)
Within RDA (1.0× RDA) 27 studies (A:0, B:11)
45 mg (900% DV)
9.0× RDA — above typical dose 2 studies — no high-quality reviews
Kale
125 mg

Other Ingredients

Cellulose Silica Stearic Acid
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: 1 tablet daily, or as directed by your healthcare practitioner. May be taken anytime throughout the day, even on an empty stomach.

Formulation Notes

Promotes healthy energy levels

Non GMO Project Verified nongmoproject.org Glyphosate Residue Free detoxproject.org Tested Gluten Free Dairy Free Soy free

Vegan

Kosher

In this INNATE Response product each vitamin or mineral is paired with an ideal whole food using our unique process to deliver guaranteed potency and the benefit of health-promoting compounds present in the whole food itself.

Additional Information

Please Recycle Vis medicatrix naturae

To learn more about our seals, please visit innateresponse.com/standards.

Certified B Corporation Non GMO Project Verified nongmoproject.org Glyphosate Residue Free detoxproject.org Tested 125+ pesticides & herbicides Tested Gluten Free Certified Vegan Vegan.org OK (Kosher)

At INNATE Response we share your belief that nothing is more important than supporting your body's innate ability to heal. To that end, we develop nutrient-rich supplements.

See how they're made at innateresponse.com/showme. Satisfaction guaranteed or your money back. Learn more at: www.innateresponse.com

Metadata

Product Details

UPC / SKU0 51494 40012 8
DSLD Entry Date2022-06-16
Product TypeBotanical with Nutrients
FormTablet or Pill
BrandInnate Response Formulas
DSLD ID267842
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.