🟢 96/100

This product looks safe

  • Ferronyl Carbonyl Iron: 125mg is 2.8× the Tolerable Upper Intake Level (45mg)
  • 80% of ingredients have research evidence
C Label Compliance Grade

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Safety Alerts

⚠️ Ferronyl Carbonyl Iron: 125mg is 2.8× the Tolerable Upper Intake Level (45mg)

Label Data

1 {Tablet(s)} Serving Size
Multi-Vitamin and Mineral (MVM) Product Type
80% Evidence Coverage

Supplement Facts — Evidence Check

Sumalate
25 mg
⚠️ Exceeds Tolerable Upper Intake Level by 2.8× (UL: 45 mg) 📚 499 studies (Tier A: 17, B: 273)
RDA 8mg This product: 125mg UL 45mg
1 mg
✅ 2.5× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 1mg UL 1.0mg
Vitamin C
160 mg
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 5mg
10 mg
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
15 mcg
📊 6.2× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.015mg
1000 IU
✅ 1.7× RDA — within safe limits 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.025mg UL 0.1mg
25 mg
✅ 2.3× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 25mg UL 40mg
15 mg
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 15mg

Other Ingredients

Black Iron Oxide Citric Acid Croscarmellose Sodium Di Calcium Phosphate Ethyl Cellulose FD&C Red #40 Lake fumed Silica Gum Arabic Hydroxypropyl Cellulose Hypromellose Magnesium Stearate Microcrystalline Cellulose Polyethylene Glycol Polysorbate 80 PVP K30 Talc Titanium Dioxide Tripotassium Citrate Vegetable oil

Label Claims — Verification

All Other
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

DOSAGE AND ADMINISTRATION Usual adult dose is 1 tablet daily, or as prescribed by a physician.

⚠️ Warnings & Precautions

WARNINGS Folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B12 is deficient.

Folic Acid Folic acid in doses above 1.0 mg daily may obscure pernicious anemia in that hematologic remission can occur while neurological manifestations remain progressive. Pernicious anemia should be excluded before using this product since folic acid may mask the symptoms of pernicious anemia.

ADVERSE REACTIONS Adverse reactions with iron therapy may include constipation, diarrhea, nausea, vomiting, dark stools and abdominal pain. Adverse reactions with iron therapy are usually transient.

Allergic sensitization has been reported following both oral and parenteral administration of folic acid.

OVERDOSAGE The clinical course of acute iron overdosage can be variable. Initial symptoms may include abdominal pain, nausea, vomiting, diarrhea, tarry stools melena, hematemesis, hypotension, tachycardia, metabolic acidosis, hyperglycemia, dehydration, drowsiness, pallor, cyanossi, lassitude, seizures, shock and coma.

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. KEEP THIS PRODUCT OUT OF THE REACH OF CHILDREN. In case of accidental overdose, call a doctor or poison control center immediately.

PRECAUTIONS General Do not exceed recommended dose. The type of anemia and the underlying cause or causes should be determined before starting therapy with CORVITE(R) FE. Since the anemia may be a result of a sytemic disturbance, such as recurrent blood loss, the underlying cause or causes should be corrected, if possible.

Pediatric Use Safety and effectiveness in pediatric patients have not been established.

Geriatric Use Clinical studies on this product have not been performed in subjects aged 65 and over to determine whether elderly subjects respond differently from younger subjects. In general, dose selection for an elderly patient should be cautious.

KEEP THIS AND ALL DRUGS OUT OF REACH OF CHILDREN.

Additional Information

PRESCRIBING INFORMATION DESCRIPTION Red, oval bisected tablets embossed "VP042".

CLINICAL PHARMCOLOGY Iron is an essential component in the formation of hemoglobin. Adequate amounts of iron are necessary for effective erythropoiesis. Iron also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Folic acid is required for nucleoprotein synthesis and the maintenance of normal erythropoiesis. Folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase. Vitamin B12 is required for the maintenance of normal erythropoiesis, nucleoprotein and myelin synthesis, cell reproduction and normal growth. Intrinsic factor, a glycoprotein secreted by the gastric mucosa, is required for active absorption of vitamin B12 from the gastrointestinal tract.

CFELB021101

STORAGE Store at controlled room temperature 15(0)-30(0)C (59(0)-86(0)F) [See USP]. Protect from light, moisture and excessive heat. Dispense in a tight, light resistant container as defined in the USP using a child-resistant closure.

Rx Only.

Product Details

DSLD Entry Date 2013-11-25
Product Type Multi-Vitamin and Mineral (MVM)
Form Tablet or Pill
DSLD ID 26580
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
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