🟢 94/100

This product looks safe

  • Niacinamide: 750mg is 21.4× the Tolerable Upper Intake Level (35mg)
  • 100% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacinamide: 750mg is 21.4× the Tolerable Upper Intake Level (35mg)

Label Data

1 Tablet(s) Serving Size
60 Servings
Multi-Vitamin and Mineral (MVM) Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

750 mg
⚠️ Exceeds Tolerable Upper Intake Level by 21.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 750mg UL 35mg
27 mg (180% DV)
✅ 2.5× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 27mg UL 40mg
500 mcg (125% DV)
✅ 1.2× RDA — within safe limits 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.5mg UL 1.0mg
2 mg (100% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
50 mcg (71% DV)
✅ Within RDA (0.9× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.05mg UL 0.4mg
100 mcg (83% DV)
✅ 2.9× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.1mg

Other Ingredients

Methocel K Anhydrous Lactose Silicon Dioxide Microcrystalline Cellulose Magnesium Stearate Hydroxypropylmethylcellulose Triacetin Titanium Dioxide

Label Claims — Verification

Nutrient
All Other
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Dosage and administration: Take 1-2 tablets daily, as a dietary supplement, as directed by your physician.

⚠️ Warnings & Precautions

Warnings: If you are pregnant, nursing, or taking medication, consult your doctor before use.

Use only under the advice and supervision of a physician if you have a history of jaundice, liver disease or diabetes. Abnormal liver function tests have been reported in persons taking daily doses of 500 mg or more of niacinamide. Folate intake should not exceed 250% of the daily value (1,000 mcg).

Keep out of the reach of children.

Do not use if seal under cap is broken or missing.

🧪 Formulation Notes

Each white-colored, oval-shaped tablet is debossed wit "342" on one side and blank on the other.

Additional Information

Store at 20 degrees - 25 degrees C (68 degrees - 77 degrees F); excursions permitted to 15 degrees - 30 degrees C (59 degrees - 86 degrees F) [See USP controlled room temperature.]

The listed product number is not a National Drug Code, but instead has merely been formatted to comply with standard industry practice for pharmacy and insurance computer systems. 758584-343-60 Rx only

Product Details

UPC / SKU 3 75854 34360 4
DSLD Entry Date 2021-12-18
Product Type Multi-Vitamin and Mineral (MVM)
Form Tablet or Pill
DSLD ID 264215
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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