CalPlex

product on market Tablet or Pill Karuna Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Calcium, phosphorus, and vitamin D3 have strong evidence supporting their roles in maintaining bone density and mineral homeostasis. Vitamin K1 and vitamin C further assist in bone mineralization and collagen synthesis. Overall, these ingredients are well-researched for skeletal health, though evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for CalPlex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
90
Servings
Multi-Vitamin and Mineral (MVM)
Product Type
50%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
150 mg (250% DV)
800 IU (200% DV)
1.3× RDA — within safe limits 608 studies (A:16, B:251)
500 mcg (625% DV)
4.2× RDA — above typical dose 275 studies (A:9, B:175)
Calcium
500 mg (50% DV)
120 mg (12% DV)
Within RDA (0.2× RDA) 13 studies (A:0, B:3)
250 mg (63% DV)
Within RDA (0.6× RDA) 316 studies (A:8, B:159)
8 mg (400% DV)
3.5× RDA — above typical dose (UL: 11 mg) 9 studies — no high-quality reviews
Microcrystalline Hydroxyapatite
1200 mg
20 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
500 mcg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Cellulose Vegetable Stearine Silicon Dioxide
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Suggested use for adults: 2-4 tablets per day, taken with meals, or as directed by your health care practitioner.

Formulation Notes

Calcium hydroxyapatite complex

This product contains no yeast, wheat, soy, milk, salt, sugar, artificial coloring, preservatives or flavoring.

This product is intended for professional use and is manufactured under strict quality control to ensure the optimum in purity, potency and reliability.

Additional Information

Keep in a cool, dry place tightly capped.

Metadata

Product Details

UPC / SKU0 18647 02104 3
DSLD Entry Date2022-05-19
Product TypeMulti-Vitamin and Mineral (MVM)
FormTablet or Pill
BrandKaruna
DSLD ID262662
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.