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Ultra B-12

product on market Liquid NOW Safety: 92/100
92/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 1333mg is 1333.0× the Tolerable Upper Intake Level (1.0mg)
  • 70% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This profile contains B-vitamins including thiamine, riboflavin, and niacin, which support cellular energy metabolism and neurological function. There is strong evidence for the role of these nutrients in maintaining metabolic health. The overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Folate: 1333mg is 1333.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Ultra B-12
Open Full PDF View on NIH DSLD →
Details

Label Data

5 mL
Serving Size
24
Servings
Vitamin
Product Type
70%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Carbohydrates
3 Gram(s) (1% DV)
3 mg (250% DV)
2.5× RDA — within safe limits 76 studies (A:0, B:33)
3.4 mg (262% DV)
2.6× RDA — within safe limits 13 studies (A:0, B:1)
50 mg (313% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
10 mg (588% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
1333 mcg DFE (333% DV)
Exceeds UL by 1333.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
5 mg (208333% DV)
2083.3× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (1000% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews

Other Ingredients

de-ionized Water Vegetable Glycerin Xylitol Malic Acid Natural Flavors organic Stevia leaf extract Potassium Sorbate Choline Bitartrate Inositol Grapefruit Cinnamon bark oil
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested usage: Shake well before use. In the morning, take 1 teaspoon, hold in mouth for 30 seconds, then swallow. Take with a meal.

Warnings & Precautions

Caution: For adults only.

Consult a physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Contains Xylitol, which is harmful to pets.

Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that process other ingredients containing these allergens.

Formulation Notes

Vitamin B-12 has the largest and most complex chemical structure of all the vitamins. It it a water-soluble vitamin with a key role in in the normal functioning of the brain and nervous system, as well as in the metabolic utilization of fats and proteins and the cellular production of energy. Vitamin B-12 is also essential for proper red blood cell production, homocysteine metabolism, and the maintenance of a healthy gastrointestinal tract.

NOW Vitamin B-12 is appropriate for vegetarians/vegans (non-animal derived), who are at higher risk of developing vitamin B-12 deficiency.

Natural color variation may occur in this product.

Pleasant tasting!!

Ultra B-12 5,000 mg of B-12 per teaspoon

Cellular energy boost

3 forms of B-12 for maximum utilization Complete liquid B-complex 800 mcg Folic acid

Triangle K (Kosher)

Vegetarian/vegan

Vitamins

Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish ingredients.

Additional Information

Refrigerate after opening to maximize freshness.

GMP Quality Assured

Triangle K (Kosher)

Family owned since 1968.

Metadata

Product Details

UPC / SKU7 33739 00452 9
DSLD Entry Date2021-02-25
Product TypeVitamin
FormLiquid
BrandNOW
DSLD ID244470
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.