B-Complex with Metafolin and Intrinsic Factor
92/100
This product looks safe
- Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
- Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
- 78% of ingredients have research evidence
D
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
1 Vegetarian Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
78%
Evidence Coverage
Supplement Facts — Evidence Check
50 mg
(4167% DV)
📊 41.7× RDA — above typical dose
📚 76 studies (Tier A: 0, B: 33)
20 mg
(1538% DV)
📊 15.4× RDA — above typical dose
📚 12 studies (Tier A: 0, B: 1)
50 mg
(250% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
20 mg
(1176% DV)
📊 15.4× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
667 mcg DFE
(167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
500 mcg
(20833% DV)
📊 208.3× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
300 mcg
(1000% DV)
📊 10.0× RDA — above typical dose
📚 26 studies (Tier A: 0, B: 11)
50 mg
(1000% DV)
📊 10.0× RDA — above typical dose
📚 1 studies — no high-quality reviews
Intrinsic Factor
20 mg
Other Ingredients
Microcrystalline Cellulose
Hydroxypropyl Methylcellulose
Vegetable Stearate
Label Claims — Verification
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (83% of products)
Nutrient (47% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
Suggested Usage: As a dietary supplement, adults take 1 capsule daily or as directed by your healthcare professional.
⚠️ Warnings & Precautions
Warning: If you are pregnant or nursing, or if you are taking prescription medications, consult your health professional before using this supplement.
Keep out of the reach of children.
Use only if safety seal is intact.
🧪 Formulation Notes
Gluten Free, Non-GMO
Energy metabolism and neurological health
Additional Information
Store in a cool, dry place.
Scan to learn about our manufacturing excellence Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.
Product Details
UPC / SKU
3 10539 03586 3
DSLD Entry Date
2020-08-23
Product Type
Other Combinations
Form
Capsule
Brand
Douglas Laboratories
DSLD ID
231838
Data Updated
2026-04-11
Research Evidence
100
Research Sources
56
Avg Quality Score
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B
Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
B
Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
B
Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
B
Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
B
Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
B
Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
B
Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
B
The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
B
Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
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